Paban Véronique, Feraud Lewis, Weills Arnaud, Duplan Fabien
CNRS-UMR 7077, CRPN, Aix Marseille Univ, Marseille, France.
Psychomotricien, Aix-en-Provence, France.
Eur J Neurosci. 2024 Dec;60(12):7164-7182. doi: 10.1111/ejn.16621. Epub 2024 Nov 26.
This study addresses the pressing issue of subjective cognitive decline in aging populations by investigating neurofeedback (NFB) as a potential early therapeutic intervention. By evaluating the efficacy of individualised NFB training compared to standard protocols, tailored to each participant's EEG profile, it provides novel insights into personalised treatment approaches. The incorporation of innovative elements and rigorous analytical techniques contributes to advancing our understanding of NFB's modulatory effects on EEG frequencies and cognitive function in aging individuals.
In the context of an aging population, concerns surrounding memory function become increasingly prevalent, particularly as individuals transition into middle age and beyond. This study investigated neurofeedback (NFB) as a potential early therapeutic intervention to address subjective cognitive decline (SCD) in aging populations. NFB, a biofeedback technique utilising a brain-computer interface, has demonstrated promise in the treatment of various neurological and psychological conditions. Here, we evaluated the efficacy of individualised NFB training, tailored to each participant's EEG profile, compared to a standard NFB training protocol aimed at increasing peak alpha frequency power, in enhancing cognitive function among individuals experiencing SCD. Our NFB protocol incorporated innovative elements, including the implementation of a criterion for learning success to ensure consistent achievement levels by the conclusion of the training sessions. Additionally, we introduced a non-learner group to account for individuals who do not demonstrate the expected proficiency in NFB regulation. Analysis of electroencephalographic (EEG) signals during NFB sessions, as well as before and after training, provides insights into the modulatory effects of NFB on EEG frequencies. Contrary to expectations, our rigorous analysis revealed that the ability of individuals with SCD to modulate EEG signal power and duration at specific frequencies was not exclusive to the intended frequency target. Furthermore, examination of EEG signals recorded using a high-density EEG showed no discernible alteration in signal power between pre- and post-NFB training sessions. Similarly, no significant effects were observed on questionnaire scores when comparing pre- and post-NFB training assessments.
本研究通过将神经反馈（NFB）作为一种潜在的早期治疗干预措施进行研究，来解决老年人群主观认知衰退这一紧迫问题。通过评估针对每位参与者脑电图特征量身定制的个性化NFB训练与标准方案相比的疗效，本研究为个性化治疗方法提供了新的见解。创新元素和严格分析技术的纳入有助于推进我们对NFB对老年个体脑电图频率和认知功能调节作用的理解。
在人口老龄化的背景下，围绕记忆功能的担忧日益普遍，尤其是当个体步入中年及以后。本研究将神经反馈（NFB）作为一种潜在的早期治疗干预措施，以解决老年人群的主观认知衰退（SCD）问题。NFB是一种利用脑机接口的生物反馈技术，在治疗各种神经和心理疾病方面已显示出前景。在此，我们评估了针对每位参与者脑电图特征量身定制的个性化NFB训练与旨在增加阿尔法峰值频率功率的标准NFB训练方案相比，在增强SCD个体认知功能方面的疗效。我们的NFB方案纳入了创新元素，包括实施学习成功标准，以确保在训练课程结束时达到一致的成就水平。此外，我们引入了一个非学习者组，以考虑那些在NFB调节方面未表现出预期熟练程度的个体。对NFB训练期间以及训练前后的脑电图（EEG）信号进行分析，有助于了解NFB对EEG频率的调节作用。与预期相反，我们的严格分析表明，SCD个体在特定频率下调节EEG信号功率和持续时间的能力并不局限于预期的频率目标。此外，使用高密度脑电图记录的EEG信号检查显示，NFB训练前后信号功率没有明显变化。同样，在比较NFB训练前后的评估问卷分数时，未观察到显著影响。
