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一项比较掌侧锁定钢板与石膏固定治疗老年桡骨远端骨折的荟萃分析。

A meta-analysis comparing volar locking plates and cast immobilization for distal radius fractures in the elderly.

机构信息

The Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.

出版信息

J Orthop Surg Res. 2024 Nov 27;19(1):795. doi: 10.1186/s13018-024-05216-7.

Abstract

BACKGROUND

The long-term outcomes (≥ 2 years of follow-up) of volar locked plate (VLP) fixation versus closed reduction and casting (CRC) for the treatment of displaced distal radial fractures (DRFs) remain unclear. This study aimed to conduct a meta-analysis comparing the long-term clinical outcomes of VLP and CRC in elderly patients (aged ≥ 60 years).

METHODS

A comprehensive search of PubMed, Web of Science, and Cochrane Library was performed to identify studies comparing the long-term outcomes of VLP and CRC for DRFs. Only randomized controlled trials (RCTs) with a mean follow-up duration of at least 2 years and participants aged 60 years or older were included. The risk of bias in the included studies was assessed. The primary outcome measure was the Patient-Rated Wrist Evaluation (PRWE). Secondary outcomes included the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire, EuroQol 5 Dimension 5-level score (EQ-5D-5 L), grip strength, and incidence of reoperation.

RESULTS

Four RCTs, comprising 423 patients, were included. The meta-analysis revealed that VLP fixation was associated with significantly improved outcomes compared to CRC in terms of PRWE score (pooled mean difference: -6.21; 95% CI: -10.28 to -2.15; p = 0.003), DASH score (pooled mean difference: -8.18; 95% CI: -13.35 to -3.01; p = 0.002), and grip strength (pooled mean difference: -6.63; 95% CI: 0.25 to 13.01; p = 0.04). There were no significant differences in EQ-5D-5 L score (95% CI: -0.08 to 0.05; p = 0.74) or incidence of reoperation (RR = 0.56; 95% CI: 0.22 to 1.42; p = 0.22).

CONCLUSIONS

A two-year follow-up of displaced DRFs in elderly patients showed no significant long-term clinical advantage of VLP fixation over CRC.

摘要

背景

掌侧锁定钢板(VLP)固定与闭合复位和石膏固定(CRC)治疗桡骨远端骨折(DRF)的长期(≥2 年随访)结果仍不清楚。本研究旨在进行一项荟萃分析,比较 VLP 和 CRC 在老年患者(≥60 岁)治疗 DRF 的长期临床结果。

方法

全面检索 PubMed、Web of Science 和 Cochrane Library,以确定比较 VLP 和 CRC 治疗 DRF 的长期结果的研究。仅纳入平均随访时间至少 2 年且参与者年龄≥60 岁的随机对照试验(RCT)。评估纳入研究的偏倚风险。主要结局测量指标为患者腕关节评估量表(PRWE)。次要结局指标包括上肢功能障碍问卷(DASH)问卷、欧洲五维健康量表 5 级评分(EQ-5D-5 L)、握力和再手术发生率。

结果

纳入了 4 项 RCT,共 423 名患者。荟萃分析显示,与 CRC 相比,VLP 固定在 PRWE 评分(合并均数差:-6.21;95%置信区间:-10.28 至 -2.15;p=0.003)、DASH 评分(合并均数差:-8.18;95%置信区间:-13.35 至 -3.01;p=0.002)和握力(合并均数差:-6.63;95%置信区间:0.25 至 13.01;p=0.04)方面具有显著改善的结果。EQ-5D-5 L 评分(95%置信区间:-0.08 至 0.05;p=0.74)或再手术发生率(RR=0.56;95%置信区间:0.22 至 1.42;p=0.22)无显著差异。

结论

对老年患者的桡骨远端骨折进行 2 年随访,VLP 固定与 CRC 相比在临床方面没有明显的长期优势。

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