Morita R, Fukunaga M, Otsuka N
Gan No Rinsho. 1986 Jan;Suppl:163-76.
At present, scintigraphic studies of bone, liver and lymph node have widely been in assessment of metastasis due to breast cancer. Bone scintigraphy is sensitive in the detection of bone metastasis. However, it has also a demerit of high false positive rate. In order to exclude this possibility, bone marrow scintigraphy using 99mTc-Re-colloid is used. Bone marrow scintigraphy is able to differentiate bone metastasis from benign bone lesion and to clarify the intra-medullary metastasis. Liver scintigraphy associated with emission CT gives better detectability of SOL due to liver metastasis. Radionuclide lymphography is used for the visualization of parasternal lymph nodes, and for the evaluation of lymph nodes metastasis. Labelled estrogen as receptor imaging has been tried to delineate breast cancer itself or metastatic focus, but is remained to be further investigated.
目前，骨、肝和淋巴结的闪烁扫描研究已广泛应用于乳腺癌转移的评估。骨闪烁扫描在检测骨转移方面很敏感。然而，它也有假阳性率高的缺点。为了排除这种可能性，使用99mTc-锝胶体进行骨髓闪烁扫描。骨髓闪烁扫描能够区分骨转移和良性骨病变，并明确髓内转移情况。与发射型CT相关的肝脏闪烁扫描对肝转移所致的肝脏占位性病变（SOL）具有更好的检测能力。放射性核素淋巴造影用于胸骨旁淋巴结的显影以及淋巴结转移的评估。标记雌激素作为受体显像已尝试用于描绘乳腺癌本身或转移灶，但仍有待进一步研究。
