Sakamoto G, Sugano H, Fukami A, Kuno K
Gan No Rinsho. 1986 Jan;Suppl:229-37.
We analyzed the association of obesity with case distribution and prognosis of breast cancer. We obtained the following results by using 1,587 breast cancer cases mastectomized between 1965 and 1974 at the Cancer Institute Hospital, Tokyo. 1) Non-invasive ductal carcinoma was prominent in non-obese patients. 2) The ratio of obese group was increasing as the patients became older. 3) Obese patients had bigger size of tumor and more advanced lymph node metastasis than non-obese patients. 4) In premenopausal patients but not in postmenopausal ones, obese group showed poorer 5-year survival rate than non-obese group (p less than 0.01), and it was true even after equalizing the tumor size and lymph node metastasis.
我们分析了肥胖与乳腺癌病例分布及预后之间的关联。通过对1965年至1974年间在东京癌症研究所医院接受乳房切除术的1587例乳腺癌病例进行研究，我们得出了以下结果。1）非肥胖患者中导管原位癌较为突出。2）肥胖组的比例随着患者年龄的增长而增加。3）肥胖患者的肿瘤体积比非肥胖患者更大，淋巴结转移也更严重。4）在绝经前患者中，而非绝经后患者中，肥胖组的5年生存率低于非肥胖组（p<0.01），即使在将肿瘤大小和淋巴结转移情况进行均衡后也是如此。
