Xu Zhen, Shen Bin, Xiao Songlin, Zhang Chuyi, Zhan Jianglong, Li Jingjing, Fu Weijie, Jin Jing
School of Exercise and Health, Shanghai University of Sport, Shanghai 200438, China.
Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai 200438, China.
Bioengineering (Basel). 2024 Oct 30;11(11):1088. doi: 10.3390/bioengineering11111088.
This study systematically reviews the literature on transcranial direct current stimulation (tDCS) interventions for lower-limb endurance performance in healthy adults and provides a summary of the effects and underlying mechanisms of tDCS on lower-limb endurance performance. Systematic searches were performed in PubMed, Web of Science, EBSCO, and ScienceDirect. The risk of bias was assessed using the Cochrane risk of bias assessment tool. The electronic search totaled 341 studies. Twenty-one studies were included in the review after screening. The results show that tDCS effectively improved time to task failure (TTF), increased blood lactate accumulation, and reduced the rating of perceived exertion during cycling. However, the tDCS failed to significantly improve the TTF, relieve muscle pain, and reduce fatigue indices during single-joint fatigue tasks in the knee. Moreover, tDCS intervention caused the effective improvement of the overall lower-limb endurance performance but exerted no uniformly conclusive effect on knee endurance performance. This finding can be partly attributed to varying stimulation protocols across studies. Future studies may focus on the effects of the application of stimulation protocols, such as multitarget stimulation and personalized dosage, to develop targeted stimulation protocols.
本研究系统回顾了关于经颅直流电刺激（tDCS）干预对健康成年人下肢耐力表现影响的文献，并总结了tDCS对下肢耐力表现的作用及潜在机制。在PubMed、科学网、EBSCO和科学Direct数据库中进行了系统检索。使用Cochrane偏倚风险评估工具评估偏倚风险。电子检索共获得341项研究。经筛选，21项研究纳入综述。结果显示，tDCS有效延长了任务失败时间（TTF），增加了血乳酸积累，并降低了骑行过程中的主观用力程度。然而，在膝关节单关节疲劳任务中，tDCS未能显著改善TTF、缓解肌肉疼痛并降低疲劳指数。此外，tDCS干预有效改善了整体下肢耐力表现，但对膝关节耐力表现未产生一致的确切影响。这一发现部分可归因于各研究中不同的刺激方案。未来研究可聚焦于刺激方案应用的效果，如多靶点刺激和个性化剂量，以制定针对性的刺激方案。
