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儿童自闭症谱系障碍:早期症状与治疗干预

Autism Spectrum Disorder in Children: Early Signs and Therapeutic Interventions.

作者信息

Abualait Turki, Alabbad Maryam, Kaleem Imdad, Imran Hadia, Khan Hamid, Kiyani Mubin Mustafa, Bashir Shahid

机构信息

College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia.

Department of Medical Rehabilitation and Long-Term Care, Al-Ahsa Health Cluster, Al-Ahsa 31982, Saudi Arabia.

出版信息

Children (Basel). 2024 Oct 29;11(11):1311. doi: 10.3390/children11111311.

DOI:10.3390/children11111311
PMID:39594885
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11592467/
Abstract

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by challenges in communication, social interaction difficulties, and repetitive behaviors that can hinder a child's development. The growing prevalence of autism necessitates early detection and effective intervention strategies. This review summarizes the current knowledge of early indicators of ASD, including brain development markers and behavioral signs visible in infants. It investigates diagnostic processes, emphasizing the importance of timely detection at 18 to 24 months using established screening tools. We discuss a variety of therapeutic approaches, including behavioral interventions, educational strategies such as music therapy, and technological advancements such as speech-generating devices. Furthermore, we investigate pharmacological options for treating associated symptoms, emphasizing the lack of targeted medications for core ASD symptoms. Finally, we present evidence highlighting the positive effects of early intervention on developmental outcomes, advocating for individualized treatment plans to enhance the well-being of children with ASD. This comprehensive overview aims to inform ongoing ASD research and clinical practices.

摘要

自闭症谱系障碍(ASD)是一种复杂的神经发育疾病,其特征在于沟通方面存在挑战、社交互动困难以及重复行为,这些都会阻碍儿童的发育。自闭症患病率的不断上升使得早期检测和有效的干预策略成为必要。本综述总结了目前关于ASD早期指标的知识,包括大脑发育标志物以及婴儿身上可见的行为迹象。它研究了诊断过程,强调使用既定筛查工具在18至24个月时及时检测的重要性。我们讨论了多种治疗方法,包括行为干预、诸如音乐疗法等教育策略以及诸如语音生成设备等技术进步。此外,我们研究了治疗相关症状的药物选择,强调缺乏针对ASD核心症状的靶向药物。最后,我们展示了强调早期干预对发育结果具有积极影响的证据,倡导制定个性化治疗计划以提高ASD儿童的福祉。这一全面概述旨在为正在进行的ASD研究和临床实践提供信息。