Alférez María Dolores, Corda Andrea, de Blas Ignacio, Gago Lucas, Fernandes Telmo, Rodríguez-Piza Ignacio, Balañá Beatriz, Corda Francesca, Gómez Ochoa Pablo
VetCorner Unavets, 50012 Zaragoza, Spain.
Department of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.
Animals (Basel). 2024 Nov 16;14(22):3301. doi: 10.3390/ani14223301.
Insulinomas are the most common neoplasms of the endocrine pancreas in dogs, leading to persistent hypoglycemia due to inappropriate insulin secretion. The standard treatment is surgical resection, but it carries significant risks, including pancreatitis and diabetes mellitus. This study investigates the efficacy and safety of percutaneous ultrasound-guided radiofrequency ablation (RFA) as an alternative to surgery. A total of 29 dogs diagnosed with insulinoma were treated with RFA, targeting both primary pancreatic tumors and metastases in regional lymph nodes or the liver. Blood glucose levels and tumor size were monitored before and after the procedure. RFA led to a significant increase in blood glucose levels and a reduction in tumor size in all patients, with minimal postoperative complications. The results suggest that RFA is a feasible and effective treatment option for insulinomas in dogs.
胰岛素瘤是犬内分泌胰腺最常见的肿瘤，由于胰岛素分泌不当导致持续性低血糖。标准治疗方法是手术切除，但手术风险很大，包括胰腺炎和糖尿病。本研究调查经皮超声引导下射频消融（RFA）作为手术替代方法的有效性和安全性。共有29只诊断为胰岛素瘤的犬接受了RFA治疗，目标是原发性胰腺肿瘤以及区域淋巴结或肝脏中的转移瘤。在治疗前后监测血糖水平和肿瘤大小。RFA使所有患者的血糖水平显著升高，肿瘤大小减小，术后并发症极少。结果表明，RFA是犬胰岛素瘤可行且有效的治疗选择。
