Wien Center for Alzheimer's, Mount Sinai Medical Center, 4300 Alton Rd, Miami, FL 33140, USA.
Center for Children and Families, Florida International University, 11200 SW 8th Street, Miami, FL 33139, USA.
Int J Environ Res Public Health. 2024 Oct 24;21(11):1408. doi: 10.3390/ijerph21111408.
The mediating role of anxious, depressive, and somatic symptoms was examined in the association between adverse childhood experiences (ACEs) and adolescent substance use, with attention to the unique effects of each set of symptoms within the same model. Adolescents (n = 701) were assessed over time (ages 3-17) in a majority male (70.5%) and white (89.9%) sample. Findings indicate that depressive symptoms mediated the association between ACEs and adolescent cigarette and marijuana use. Although significant indirect effects remained when accounting for externalizing behavior, a novel protective pathway emerged through parent-reported youth anxiety and alcohol use. Assessing internalizing symptoms as separate facets within the same model is critical if we are to inform prevention programs that are tailored to the individual needs of youth who have experienced ACEs.
焦虑、抑郁和躯体症状在童年逆境经历（ACEs）与青少年物质使用之间的关联中起到了中介作用，本研究关注的是在同一模型中，每一组症状的独特影响。在一个以男性（70.5%）和白人（89.9%）为主的样本中，对 701 名青少年（年龄 3-17 岁）进行了一段时间的评估。研究结果表明，抑郁症状在 ACEs 与青少年吸烟和大麻使用之间起中介作用。尽管在考虑到外化行为时，间接效应仍然显著，但通过父母报告的青少年焦虑和酒精使用，出现了一种新的保护途径。如果我们要根据经历过 ACEs 的青少年的个体需求，为他们量身定制预防计划，那么在同一模型中评估内在症状的不同方面是至关重要的。
