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居住在夸祖鲁-纳塔尔省伊兰贝地区格伦代尔市的女性的心脏代谢性多重疾病发病风险概况。

The Cardiometabolic Multimorbidity Risk Profile of Females Living in Glendale, ILembe District of Kwa-Zulu Natal.

机构信息

Department of Sport, Rehabilitation & Dental Science, Pretoria West Campus, Tshwane University of Technology, Pretoria 0001, South Africa.

出版信息

Int J Environ Res Public Health. 2024 Oct 29;21(11):1436. doi: 10.3390/ijerph21111436.

DOI:10.3390/ijerph21111436
PMID:39595702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11593891/
Abstract

BACKGROUND

Empirical studies have indicated that cardiometabolic multimorbidity risk profiles are upsurging among the South African population. However, there is a limited number of studies that have been conducted to validate these findings in rural communities.

AIM

To study the prevalence of cardiometabolic risk factors of females residing in rural Glendale in the ILembe District, South Africa.

METHODS

One hundred females (aged 18-40 years) voluntarily participated in a cross-sectional observational study. All participants completed an ISAK somatotype profiling, and measured their fasting cholesterol, glucose, blood pressure and resting heart rate.

RESULTS

Participants' average age, body mass index, stature, and body mass, were 28.34 ± 7.07 years, 29.5 ± 8.06 kg/m, 157.26 ± 6.09 cm, and 72.9 ± 21.12 kg, respectively. The cohort had a mean waist circumference of 94.2 ± 22.1 cm, hip circumference of 108.4 ± 20.9 cm, and waist-to-hip ratio of 0.86. Participants' mean heart rate, systolic blood pressure, and diastolic blood pressure were 86.31 ± 8.68 bpm, 116.79 ± 16.34 mmHg, and 82.14 ± 10.87 mmHg, respectively. Eleven participants recorded a resting heart rate greater than 100 bpm. Average blood glucose, total cholesterol, low-density lipoprotein, and high-density lipoprotein recorded were 4.87 ± 1.26 mmol/L, 3.78 ± 0.94 mmol/L, 1.76 ± 1.86 mmol/L, and 1.31 ± 0.4 mmol/L. Eighty-three participants HDL-C were below the recommended normative value of 1.55 mmol/L.

CONCLUSION

The average participant presented as overweight, with elevated diastolic blood pressure, and a resting heart rate that has been proven to increase one's cardiometabolic multimorbidity risk profile. Additionally, a small portion of the cohort were identified to be prediabetic and diabetic. Large proportion of participants had low HDL-C levels suggestive of poor cardiovascular disease protection.

摘要

背景

实证研究表明,南非人口的心血管代谢多种疾病风险状况正在上升。然而,在农村社区中,验证这些发现的研究数量有限。

目的

研究南非伊莱姆贝地区格伦代尔农村女性的心血管代谢危险因素患病率。

方法

100 名女性(年龄 18-40 岁)自愿参加了一项横断面观察研究。所有参与者完成了 ISAK 体型分析,并测量了她们的空腹胆固醇、血糖、血压和静息心率。

结果

参与者的平均年龄、体重指数、身高和体重分别为 28.34 ± 7.07 岁、29.5 ± 8.06kg/m、157.26 ± 6.09cm 和 72.9 ± 21.12kg。该队列的平均腰围为 94.2 ± 22.1cm,臀围为 108.4 ± 20.9cm,腰臀比为 0.86。参与者的平均心率、收缩压和舒张压分别为 86.31 ± 8.68 bpm、116.79 ± 16.34mmHg 和 82.14 ± 10.87mmHg,有 11 名参与者的静息心率大于 100 bpm。平均血糖、总胆固醇、低密度脂蛋白和高密度脂蛋白分别为 4.87 ± 1.26mmol/L、3.78 ± 0.94mmol/L、1.76 ± 1.86mmol/L 和 1.31 ± 0.4mmol/L。83 名参与者的 HDL-C 低于推荐的 1.55mmol/L 正常值。

结论

平均参与者表现为超重,舒张压升高,静息心率升高,这已被证明会增加心血管代谢多种疾病的风险状况。此外,一小部分队列被确定为糖尿病前期和糖尿病患者。大部分参与者的 HDL-C 水平较低,提示心血管疾病保护不良。

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