Badrov Marija, Marovic Danijela, Tadin Antonija
Department of Restorative Dental Medicine and Endodontics, Study of Dental Medicine, School of Medicine, University of Split, 21000 Split, Croatia.
Department of Endodontics and Restorative Dental Medicine, University of Zagreb School of Dental Medicine, 10000 Zagreb, Croatia.
Antibiotics (Basel). 2024 Nov 8;13(11):1061. doi: 10.3390/antibiotics13111061.
The non-specific prescription of antibiotics, especially in dentistry, contributes to the global problem of antimicrobial resistance and highlights the need for education on the proper use and serious consequences of overprescribing these drugs. The main objective of this study is to assess and evaluate antibiotic knowledge and prescribing patterns in dental practice in Croatia, Bosnia and Herzegovina, and Serbia, focusing on understanding the rationale for prescribing, adherence to evidence-based guidelines, and dentists' awareness of antibiotic resistance.
A total of 795 dentists participated in this electronic cross-sectional survey (Croatia N = 336, Bosnia and Herzegovina N = 176, and Serbia N = 283). The study utilized a self-structured questionnaire to collect data on various aspects of antibiotic use, including knowledge, prescribing practices, awareness of guidelines, and demographic and professional information about dentists. Data analysis included the Mann-Whitney test, the Kruskal-Wallis test with post hoc analysis, and chi-square tests, with statistical significance set at < 0.05.
The overall score for the participants' knowledge of antibiotics was 6.40 ± 1.40 out of a maximum of eight points, which indicates a generally good level of knowledge among dentists. Factors such as gender, specialty, and practice location significantly influenced the level of knowledge ( < 0.05). However, actual prescribing practice was a cause for concern. Only 66.1% of Croatian dentists felt they had received adequate training during their studies, and even fewer in Serbia (48.4%) and Bosnia (46.6%). It is noteworthy that 9.7% of dentists in Bosnia and Herzegovina prescribe antibiotics at the request of patients, while 22.3% of Croatian and 25.4% of Serbian dentists do so. Many dentists prescribe no or only one antibiotic per week. In addition, 50.9% of Croatian dentists reported adverse effects related to the use of antibiotics, while only 31.3% of Bosnian and 33.6% of Serbian dentists reported similar experiences.
While the study results indicate that dentists in the region generally possess good knowledge of antibiotic use, there are significant discrepancies between this knowledge and actual prescribing practices. This highlights the need for enhanced educational programs and awareness initiatives focused on proper antibiotic guidelines to improve prescribing behaviors.
抗生素的非特异性处方，尤其是在牙科领域，加剧了全球抗菌药物耐药性问题，并凸显了开展关于正确使用这些药物以及过度处方的严重后果的教育的必要性。本研究的主要目的是评估和评价克罗地亚、波斯尼亚和黑塞哥维那以及塞尔维亚牙科实践中对抗生素的知识和处方模式，重点是理解处方的基本原理、对循证指南的遵循情况以及牙医对抗生素耐药性的认识。
共有795名牙医参与了这项电子横断面调查（克罗地亚336名，波斯尼亚和黑塞哥维那176名，塞尔维亚283名）。该研究采用自行设计的问卷来收集有关抗生素使用各个方面的数据，包括知识、处方实践、对指南的认识以及牙医的人口统计学和专业信息。数据分析包括曼 - 惠特尼检验、进行事后分析的克鲁斯卡尔 - 沃利斯检验以及卡方检验，设定统计学显著性水平为<0.05。
参与者对抗生素知识的总体得分在满分8分中为6.40±1.40，这表明牙医总体上具有较好的知识水平。性别、专业和执业地点等因素显著影响知识水平（<0.05）。然而，实际处方实践令人担忧。只有66.1%的克罗地亚牙医认为他们在学习期间接受了充分的培训，塞尔维亚（48.4%）和波斯尼亚（46.6%）的比例更低。值得注意的是，9.7%的波斯尼亚和黑塞哥维那牙医应患者要求开具抗生素，而克罗地亚为22.3%，塞尔维亚为25.4%。许多牙医每周开具的抗生素为零或仅一种。此外，50.9%的克罗地亚牙医报告了与使用抗生素相关的不良反应，而波斯尼亚只有31.3%，塞尔维亚为33.6%的牙医报告了类似经历。
虽然研究结果表明该地区的牙医总体上对抗生素使用有较好的知识，但这种知识与实际处方实践之间存在显著差异。这凸显了需要加强以适当抗生素指南为重点的教育项目和提高认识的举措，以改善处方行为。
