Suppr超能文献

肝硬化患者的心理性肝性脑病测试和脑电图结果。

Psychometric Hepatic Encephalopathy Tests and Electroencephalogram Results Among Cirrhotic Patients.

机构信息

Department of Tropical Medicine, Faculty of Medicine, Beni-Suef University, Beni-Suef 62521, Egypt.

Department of Clinical Neurophysiology (Neurodiagnostics and Research Centre), Faculty of Medicine, Beni-Suef University, Beni-Suef 62521, Egypt.

出版信息

Medicina (Kaunas). 2024 Nov 14;60(11):1861. doi: 10.3390/medicina60111861.

Abstract

: Patients with cirrhosis who seem normal during physical examinations may still have abnormalities in their electroencephalogram (EEG) or show pathological results in neuropsychological tests. This study aimed to investigate the progression of minimal hepatic encephalopathy, its effects on quality of life, its prognostic value, and its significance for daily functioning. : This study involved 50 patients with confirmed cirrhosis (28 Child A, 12 Child B, 10 Child C) who were assessed for psychological symptoms and underwent several tests: the Minimal Mental State Examination (MMSE), the Letter Cancellation Test, the Digit Symbol Coding Test, and EEG. : showed that 40% of patients exhibited neuropsychiatric symptoms, with somatization being the most common at 96%. The MMSE revealed cognitive impairment in 48% of patients. In the Letter Cancellation Test (LCT) (total error), 80% of patients had organic disorders, and 24% showed affections with (LCT) (completion time). The Digit Symbol Coding Test results showed affection in 28% of patients. Significant EEG changes were observed in patients with Child C cirrhosis. Patients with portal hypertension (including varices and variceal bleeding), liver cell failure symptoms (such as ascites, lower limb edema, and bleeding tendency), as well as those who smoke, or obese, or have hyperlipidemia, all displayed notable EEG and psychological test abnormalities, making them more likely to develop hepatic encephalopathy. : psychological testing and EEG changes are effective in detecting minimal hepatic encephalopathy, with a higher incidence in Child C patients compared to those in Child A and B.

摘要

患者在体格检查中看似正常,但他们的脑电图(EEG)可能存在异常,或者神经心理学测试显示病理性结果。本研究旨在探讨轻微肝性脑病的进展、对生活质量的影响、预后价值及其对日常功能的意义。

本研究纳入了 50 例确诊肝硬化患者(28 例 Child A、12 例 Child B、10 例 Child C),评估他们的心理症状,并进行了多项测试:简易精神状态检查(MMSE)、字母删除测试、数字符号编码测试和 EEG。

结果显示,40%的患者出现神经精神症状,以躯体化症状最为常见(96%)。MMSE 显示 48%的患者存在认知障碍。在字母删除测试(LCT)(总错误)中,80%的患者存在器质性障碍,24%的患者 LCT(完成时间)受到影响。数字符号编码测试结果显示 28%的患者受到影响。Child C 肝硬化患者的 EEG 变化明显。有门静脉高压(包括静脉曲张和静脉曲张出血)、肝细胞衰竭症状(如腹水、下肢水肿和出血倾向)、吸烟、肥胖或高血脂的患者,EEG 和心理测试异常明显,更容易发生肝性脑病。

心理测试和 EEG 变化可有效检测轻微肝性脑病,Child C 患者的发生率高于 Child A 和 B 患者。

相似文献

5
Screening of subclinical hepatic encephalopathy.亚临床肝性脑病的筛查
J Hepatol. 2000 May;32(5):748-53. doi: 10.1016/s0168-8278(00)80243-3.
9
The prognostic significance of subclinical hepatic encephalopathy.亚临床肝性脑病的预后意义。
Am J Gastroenterol. 2000 Aug;95(8):2029-34. doi: 10.1111/j.1572-0241.2000.02265.x.
10
Neuropsychological-neurophysiological alterations and brain atrophy in cirrhotic patients.
Metab Brain Dis. 2003 Mar;18(1):63-78. doi: 10.1023/a:1021982719654.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验