Rosenfeld H, Sherman R
Lasers Surg Med. 1986;6(1):20-3, 50-1. doi: 10.1002/lsm.1900060107.
This study intends to document and evaluate the first compiled experience in the treatment of both cutaneous and deep vascular lesions using the Nd:YAG laser. Thirty-eight patients were treated over a 5-year period from 1979 to 1984 using the Nd:YAG laser with FDA approval. Lesions included capillary, cavernous, combined capillary-cavernous hemangiomas, portwine stains, arteriovenous malformations, lymphangiomas, multiple telangiectasias, and one case of Klippel-Trenaunay-Webber syndrome. The number of treatments per patient ranged from one to four. Partial or complete resolution of these various lesions, as evidenced by a decrease in size, and/or normalization of pathologic cutaneous changes was noted in a majority of patients. While both the argon and CO2 lasers have been well studied in the treatment of cutaneous vascular lesions, this is the first compiled series reporting results using the Nd:YAG for such problems. The Nd:YAG laser represents an alternative modality in the treatment of cutaneous hemangiomas and introduces an efficacious method in the treatment of cavernous vascular lesions.
本研究旨在记录和评估使用钕钇铝石榴石激光治疗皮肤和深部血管病变的首次汇总经验。1979年至1984年的5年间，38例患者使用经美国食品药品监督管理局（FDA）批准的钕钇铝石榴石激光进行了治疗。病变包括毛细血管瘤、海绵状血管瘤、毛细-海绵状混合型血管瘤、葡萄酒色斑、动静脉畸形、淋巴管瘤、多发性毛细血管扩张症，以及1例克-特-韦综合征。每位患者的治疗次数为1至4次。大多数患者的这些不同病变出现了部分或完全消退，表现为大小减小和/或皮肤病理改变恢复正常。虽然氩激光和二氧化碳激光在治疗皮肤血管病变方面已有充分研究，但这是首个使用钕钇铝石榴石激光治疗此类问题的汇总系列报告。钕钇铝石榴石激光是治疗皮肤血管瘤的另一种方式，并且为治疗海绵状血管病变引入了一种有效的方法。
