Volf Jiri, Faldynova Marcela, Matiasovicova Jitka, Sebkova Alena, Karasova Daniela, Prikrylova Hana, Havlickova Hana, Rychlik Ivan
Veterinary Research Institute, 621 00 Brno, Czech Republic.
Microorganisms. 2024 Oct 25;12(11):2145. doi: 10.3390/microorganisms12112145.
There are extensive differences in the caecal microbiota of chicks from hatcheries and those inoculated with faecal material from adult hens. Besides differences in microbial composition, the latter chickens are highly resistant to Enteritidis challenges, while the former are susceptible. In this study, we tested whether strains from genera , or can increase chicken resistance to and when defined microbial mixtures consisting of these bacterial genera are administered. Mixtures consisting of different species and strains from the above-mentioned genera efficiently colonised the chicken caecum and increased chicken resistance to by a factor of 50. The tested mixtures were even more effective in protecting chickens from in a seeder model of infection (3-5 log reduction). The tested mixtures partially protected chickens from infection, though the effect was lower than that against . The obtained data represent a first step for the development of a new type of probiotics for poultry.
孵化场雏鸡与接种成年母鸡粪便的雏鸡的盲肠微生物群存在广泛差异。除了微生物组成不同外，后一种鸡对肠炎沙门氏菌的挑战具有高度抗性，而前一种则易感。在本研究中，我们测试了当施用由这些细菌属组成的特定微生物混合物时，来自 、 或 属的菌株是否能提高鸡对 和 的抗性。由上述属的不同物种和菌株组成的混合物有效地定殖于鸡的盲肠，并将鸡对 的抗性提高了50倍。在感染播种模型中，测试混合物在保护鸡免受 感染方面甚至更有效（降低3 - 5个对数）。测试混合物对鸡免受 感染有部分保护作用，尽管效果低于对 的保护作用。所获得的数据代表了开发新型家禽益生菌的第一步。
