Xu Gang, Wu Weihuai, Zhu Liqian, Liang Yanqiong, Liang Minli, Tan Shibei, Chen Helong, Huang Xing, He Chunping, Lu Ying, Yi Kexian, Ma Xiang
Pathogenesis and Control of Pathogenic Microorganisms Research Team, School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou 570228, China.
Hainan Key Laboratory for Monitoring and Control of Tropical Agricultural Pests, Environment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
Microorganisms. 2024 Nov 7;12(11):2255. doi: 10.3390/microorganisms12112255.
-induced crop diseases, commonly known as "plant plagues", pose a significant threat to global food security. In this study, strain ASG80 was isolated from sisal roots and demonstrated a broad-spectrum antagonistic activity against several species and fungal pathogens. Strain ASG80 was identified as via phylogenetic analysis, digital DNA-DNA hybridization (dDDH), and average nucleotide identity (ANI). Whole-genome sequencing identified 40 biosynthetic gene clusters (BGCs) related to secondary metabolite production, including antimicrobial compounds. Strain ASG80 extract exhibited broad-spectrum inhibitory activity against , , , and . Pot experiments showed that strain ASG80 extract significantly reduced sisal zebra disease incidence, with an efficacy comparable to the fungicide metalaxyl. These findings suggest that strain ASG80 is a promising biocontrol agent with substantial potential for managing Phytophthora-related diseases in agriculture.
由……引起的作物病害，通常被称为“植物瘟疫”，对全球粮食安全构成重大威胁。在本研究中，ASG80菌株从剑麻根系中分离得到，并对多种细菌和真菌病原体表现出广谱拮抗活性。通过系统发育分析、数字DNA-DNA杂交（dDDH）和平均核苷酸同一性（ANI）鉴定出ASG80菌株。全基因组测序确定了40个与次级代谢产物产生相关的生物合成基因簇（BGC），包括抗菌化合物。ASG80菌株提取物对……、……、……和……表现出广谱抑制活性。盆栽试验表明，ASG80菌株提取物显著降低了剑麻斑马病的发病率，其防治效果与杀菌剂甲霜灵相当。这些发现表明，ASG80菌株是一种有前途的生物防治剂，在农业中管理与疫霉相关的病害具有巨大潜力。 （原文部分内容缺失，翻译可能存在部分不连贯）
