[99mTc和133mIn标记的氨基亚甲基膦酸盐用于骨骼闪烁显像可能性的实验评估]
[Experimental evaluation of the the possible use of 99mTc- and 133mIn-labelled aminomethylene phosphonates for skeletal scintigraphy].
作者信息
Sedov V V, Starovoĭtova L P, Ovdienko N I, Liaginskaia A M, Kodina G E
出版信息
Med Radiol (Mosk). 1986 Mar;31(3):13-7.
PMID:3959792
Abstract
The pharmacokinetics of 99mTc and 113mIn labeled aminopolymethyl phosphonic acids was studied in experiments on animals. Noticeable osteotropism of these compounds was shown. Scans of the rabbit and rat skeleton in health and experimental pathology 1 h after i.v. administration of these compounds were obtained making it possible to reveal the affected foci.
摘要
在动物实验中研究了99mTc和113mIn标记的氨基聚甲基膦酸的药代动力学。结果显示这些化合物具有明显的亲骨性。静脉注射这些化合物1小时后，获得了正常和实验性病理状态下兔和大鼠骨骼的扫描图像，从而能够发现病变部位。
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