Mleczko Mateusz, Gerkowicz Agnieszka, Krasowska Dorota
Department of Dermatology, Venerology and Pediatric Dermatology, Medical University of Lublin, 11 Staszica St., 20-081 Lublin, Poland.
J Clin Med. 2024 Nov 20;13(22):6991. doi: 10.3390/jcm13226991.
: The risk of asthma in patients with psoriasis and that of psoriasis in patients with asthma have increased, but relevant data for the pediatric population are lacking. Therefore, we performed a meta-analysis to assess the pooled association between psoriasis and asthma in children and adolescents. : We conducted an extensive search of the medical literature databases through to July 2024. The estimated risk ratios (RRs) and corresponding 95% confidence intervals (CIs) were computed. : Three studies, involving 5310 children with psoriasis and 1,539,029 control participants, were included to evaluate the incidence of asthma in children with psoriasis. The meta-analysis indicated a significantly increased risk of asthma in children with psoriasis [RR 1.38 (95% CI, 1.28-1.49)]. Additionally, two studies involving 104,369 asthmatic children and 1,539,029 controls were included to evaluate the incidence of psoriasis in children with asthma. The meta-analysis indicated a significant increase in the risk of psoriasis in children with asthma [RR 1.17 (95% CI, 0.70-1.95)]. : This meta-analysis offers evidence supporting the association between psoriasis and asthma in pediatric populations. Therefore, physicians should make patients aware of the connection between these two chronic diseases.
银屑病患者患哮喘的风险以及哮喘患者患银屑病的风险均有所增加，但缺乏儿科人群的相关数据。因此，我们进行了一项荟萃分析，以评估儿童和青少年中银屑病与哮喘之间的合并关联。
我们对截至2024年7月的医学文献数据库进行了广泛检索。计算了估计风险比（RRs）及相应的95%置信区间（CIs）。
纳入了三项研究，涉及5310名银屑病儿童和1539029名对照参与者，以评估银屑病儿童中哮喘的发病率。荟萃分析表明，银屑病儿童患哮喘的风险显著增加[RR 1.38（95%CI，1.28 - 1.49）]。此外，纳入了两项研究，涉及104369名哮喘儿童和1539029名对照，以评估哮喘儿童中银屑病的发病率。荟萃分析表明，哮喘儿童患银屑病的风险显著增加[RR 1.17（95%CI，0.70 - 1.95）]。
这项荟萃分析提供了支持儿科人群中银屑病与哮喘之间关联的证据。因此，医生应让患者了解这两种慢性病之间的联系。
