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脂肪性肌肉减少症:一种与身体成分分类相关临床状况的新术语。

Steatosarcopenia: A New Terminology for Clinical Conditions Related to Body Composition Classification.

作者信息

Michels Glaycon, Mattos Rosa Guido, Renke Guilherme, Starling-Soares Bernardo

机构信息

IGM-Instituto Dr. Glaycon Michels, Florianópolis 88034-050, SC, Brazil.

Nutrindo Ideais Performance and Nutrition Research Center, Rio de Janeiro 22411-040, ES, Brazil.

出版信息

Life (Basel). 2024 Oct 28;14(11):1383. doi: 10.3390/life14111383.

Abstract

Body composition analysis focuses on measuring skeletal muscle mass and total body fat. The loss of muscle function and mass is related to clinical conditions such as frailty, increased risk of falls, and prolonged hospitalizations. Despite the relevance of the definition of sarcopenic obesity, there is still a gap in the monitoring of patients who have the combination of sarcopenia and myosteatosis, regardless of the presence of obesity. Therefore, we propose a new nomenclature, steatosarcopenia, a condition characterized by the loss of mass or skeletal muscle strength and performance associated with the excessive deposition of ectopic reserve fat in muscle tissue, in the same individual, not necessarily related to excess fat total body mass. A greater understanding of this condition may assist in developing strategies for preventing and treating metabolic diseases.

摘要

身体成分分析侧重于测量骨骼肌质量和全身脂肪。肌肉功能和质量的丧失与诸如身体虚弱、跌倒风险增加和住院时间延长等临床状况相关。尽管肌少症性肥胖的定义具有相关性,但对于同时患有肌少症和肌脂肪变性(无论是否存在肥胖)的患者的监测仍存在差距。因此,我们提出了一种新的命名法——脂肪性肌少症,这是一种在同一个体中,其特征为肌肉质量或骨骼肌力量及功能丧失,同时伴有肌肉组织中异位储备脂肪过度沉积的病症,不一定与全身脂肪过多相关。对这种病症的更深入了解可能有助于制定预防和治疗代谢性疾病的策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cac7/11595699/1c6b68207993/life-14-01383-g001.jpg

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