Zhang Runqian, Wang Jiaxin, Xi Huijuan, Cheng Yue, Han Bei
Health Science Center, Xi'an Jiaotong University, Xi'an, China.
School of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
Front Nutr. 2025 May 16;12:1579572. doi: 10.3389/fnut.2025.1579572. eCollection 2025.
This study aimed to evaluate the current research landscape, identify emerging areas of interest, and provide scientific insights for further research in exercise and nutrition for sarcopenia.
A comprehensive bibliometric analysis was conducted using publications retrieved from the Web of Science Core Collection and SCOPUS between January 1, 2005 and January 1, 2025, focusing on exercise and nutritional interventions for sarcopenia. CiteSpace and VOSviewer were employed to visualize research trends through analysis of annual publications, keyword evolution, journal contributions, author networks, country/regional distributions, institutional collaborations, citation patterns, and high-frequency terminology.
The analysis included 886 publications demonstrating a consistent upward trajectory in annual output. Geographical shifts revealed a transition of research leadership from traditional centers in the United States and Europe to emerging Asian contributors, particularly China. High-frequency keywords analysis identified core concepts including "Skeletal Muscle" (Betweenness Centrality Degree, BCD 0.13), "Resistance Exercise" (BCD 0.11), and "Muscle Strength" (BCD 0.13), with nutritional components "Dietary Protein" (BCD 0.19), "Vitamin D" (BCD 0.14), and "Amino Acids" (BCD 0.18) forming distinct research clusters. Cluster analysis revealed five thematic domains: Protein Metabolism (Cluster 1), Body Composition Assessment (Cluster 2), Resistance Training Modalities (Cluster 3), Frailty Syndromes (Cluster 4), and Metabolic Regulation (Cluster 5). Temporal keyword evolution showed a paradigm shift from foundational terms ("human skeletal muscle", "amino acids") to clinical outcome measures ("gait speed," "physical function," "inflammation") and mechanisms.
The research trend in sarcopenia is currently shifting from symptoms to underlying mechanisms. Meanwhile, the focus of exercise and nutritional interventions for sarcopenia is moving toward addressing the disease burden and health management of multiple chronic diseases associated with sarcopenia.
本研究旨在评估当前的研究状况，确定新出现的研究热点领域，并为肌肉减少症的运动与营养方面的进一步研究提供科学见解。
利用2005年1月1日至2025年1月1日期间从科学引文索引核心合集（Web of Science Core Collection）和Scopus数据库检索到的出版物进行全面的文献计量分析，重点关注肌肉减少症的运动和营养干预措施。使用CiteSpace和VOSviewer通过分析年度出版物、关键词演变、期刊贡献、作者网络、国家/地区分布、机构合作、引文模式和高频术语来可视化研究趋势。
该分析纳入了886篇出版物，显示出年产出呈持续上升趋势。地理转移表明研究主导地位从美国和欧洲的传统中心转向新兴的亚洲贡献者，尤其是中国。高频关键词分析确定了核心概念，包括“骨骼肌”（中介中心性程度，BCD 0.13）、“抗阻运动”（BCD 0.11）和“肌肉力量”（BCD 0.13），营养成分“膳食蛋白质 ”（BCD 0.19）、“维生素D”（BCD 0.14）和“氨基酸”（BCD 0.18）形成了不同的研究集群。聚类分析揭示了五个主题领域：蛋白质代谢（集群1）、身体成分评估（集群2）、抗阻训练方式（集群3）、衰弱综合征（集群4）和代谢调节（集群5）。关键词随时间的演变显示出从基础术语（“人类骨骼肌”、“氨基酸”）到临床结局指标（“步态速度”、“身体功能”、“炎症”）和机制的范式转变。
肌肉减少症的研究趋势目前正从症状转向潜在机制。同时，肌肉减少症的运动和营养干预重点正朝着解决与肌肉减少症相关的多种慢性病的疾病负担和健康管理方向发展。
