Fujimura S, Imai T, Kondo T, Handa M, Yamauchi A, Okabe T, Nadada T
Nihon Geka Gakkai Zasshi. 1986 Jan;87(1):84-8.
Fifty-eight patients have undergone bronchoplastic surgery for lung cancer and were reviewed in an attempt to evaluate its postoperative survival rate and to establish a certain method to prevent postoperative complications. Five-year survival rates of the patients with the reconstructive surgery were 36.9, 66.6, 7.9 per cent in over-all patients, stage I and II patients, and stage III patients, respectively. These results can compare favorable with the results obtained in patients who underwent standard operation for lung cancer. Seven of 9 patients with sleeve lobectomy and pulmonary artery reconstruction died within 2 years and 7 months postoperatively, and 4 of them showed distant metastasis. This type of operation may be alternative to pneumonectomy only when pneumonectomy would not be tolerated because of low cardiopulmonary reserve. Six of 8 patients died within 3 years after carina reconstruction. In this type of operation 4 cases showed tumor relapse around anastomotic site. Including 4 patients with carina reconstruction, 8 cases revealed postoperative local tumor recurrence despite the tumor free bronchial stump by frozen sections. These results indicate that prophylactic radiation therapy may be necessary to prevent local tumor relapse after the reconstructive surgery for the advanced lung cancer patients.
58例肺癌患者接受了支气管成形手术,并进行了回顾性研究,以评估其术后生存率,并建立预防术后并发症的特定方法。接受重建手术患者的5年生存率在总体患者、Ⅰ期和Ⅱ期患者以及Ⅲ期患者中分别为36.9%、66.6%和7.9%。这些结果与接受肺癌标准手术患者的结果相比具有优势。9例行袖状肺叶切除术和肺动脉重建术的患者中有7例在术后2年7个月内死亡,其中4例出现远处转移。仅当因心肺储备功能低下而无法耐受肺切除术时,这种手术类型才可作为肺切除术的替代方案。8例行隆突重建术的患者中有6例在术后3年内死亡。在这种手术类型中,4例在吻合部位周围出现肿瘤复发。包括4例行隆突重建术的患者在内,8例患者尽管冰冻切片显示支气管残端无肿瘤,但仍出现术后局部肿瘤复发。这些结果表明,对于晚期肺癌患者,预防性放射治疗可能是预防重建手术后局部肿瘤复发所必需的。