c306 GAL4并不特异于卵巢细胞。
c306 GAL4 is not specific to ovarian cells.
作者信息
Goll Ashley C, Bex Kaden H, Tootle Tina L
机构信息
Biology, University of Iowa, Iowa City, Iowa, United States.
出版信息
MicroPubl Biol. 2024 Nov 11;2024. doi: 10.17912/micropub.biology.001383. eCollection 2024.
A widely used genetic tool in is the GAL4/UAS system. This bipartite system allows for tissue and cell-specific expression and is used for both overexpression and RNA interference (RNAi) knockdown studies. Here we provide evidence that c306 GAL4 expression is not restricted to somatic ovarian cells but is also expressed in cells giving rise to adult bristles. Future work is needed to fully define the cell-specific expression pattern c306 GAL4.
果蝇中广泛使用的一种基因工具是GAL4/UAS系统。这个二元系统允许组织和细胞特异性表达，并且用于过表达和RNA干扰（RNAi）敲低研究。在这里，我们提供证据表明，c306 GAL4的表达不仅限于卵巢体细胞，还在产生成虫刚毛的细胞中表达。需要进一步的研究来全面确定c306 GAL4的细胞特异性表达模式。
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