Department of Neurology, Affiliated ZhongDa Hospital, Southeast University, Nanjing, China.
Department of Neurology, Xishan People's Hospital of Wuxi City, Wuxi, China.
Sleep Breath. 2024 Nov 27;29(1):14. doi: 10.1007/s11325-024-03169-z.
The main objective of this meta-analysis was to assess the accuracy of the Sleep-Related Breathing Disorder (SRBD) Scale in the diagnosis of obstructive sleep apnea syndrome (OSAS).
A comprehensive review and meta-analysis of observational studies evaluating the diagnostic utility of OSA screening questionnaires were performed. Analyses determined the summary receiver operator characteristic area under the curve (SROC), the pooled sensitivity (Se), and the specificity (Sp). Subgroup analysis investigated and compared the summary sensitivity, specificity, and diagnostic odds ratio (DOR) among the BQ, STOP, and ESS according to the severity of OSA.
34 studies were included. The Berlin questionnaire had a sensitivity of 0.80 and a specificity of 0.48, while the Epworth sleepiness scale had a sensitivity of 0.48 and a specificity of 0.73. The STOP-BANG scale had a sensitivity and specificity of 0.89 and 0.40, respectively. The diagnostic accuracy of BQ, ESS, NoSAS, and STOP was evaluated based on OSA severity. BQ and STOP had higher sensitivity and specificity, while ESS had lower specificity.
The current meta-analysis indicates that the SRBD scale has acceptable accuracy in detecting patients with OSAS. We propose that the STOP questionnaire could be used as an easy-to-use and accurate screening tool for the identification of patients at risk for OSAS in the general population. ESS had higher specificity, allowing healthcare professionals to prioritize interventions and tailor treatment plans based on OSA severity.
本荟萃分析的主要目的是评估睡眠相关呼吸障碍（SRBD）量表在诊断阻塞性睡眠呼吸暂停综合征（OSAS）中的准确性。
对评估 OSA 筛查问卷诊断效用的观察性研究进行了全面的综述和荟萃分析。分析确定了汇总接收者操作特征曲线下面积（SROC）、汇总敏感性（Se）和特异性（Sp）。亚组分析根据 OSAS 的严重程度，调查并比较了 BQ、STOP 和 ESS 的汇总敏感性、特异性和诊断优势比（DOR）。
共纳入 34 项研究。柏林问卷的敏感性为 0.80，特异性为 0.48，而 Epworth 嗜睡量表的敏感性为 0.48，特异性为 0.73。STOP-BANG 量表的敏感性和特异性分别为 0.89 和 0.40。根据 OSAS 的严重程度评估了 BQ、ESS、NoSAS 和 STOP 的诊断准确性。BQ 和 STOP 的敏感性和特异性较高，而 ESS 的特异性较低。
本荟萃分析表明，SRBD 量表在检测 OSAS 患者方面具有可接受的准确性。我们建议 STOP 问卷可作为一种简单易用且准确的筛查工具，用于识别一般人群中患有 OSAS 风险的患者。ESS 具有较高的特异性，使医疗保健专业人员能够根据 OSAS 的严重程度优先干预和制定治疗计划。
