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老年人阻塞性睡眠呼吸暂停的筛查:以多导睡眠图为金标准评估柏林问卷、STOP-Bang问卷及爱泼华嗜睡量表的效能

Screening for obstructive sleep apnea in elderly: performance of the Berlin and STOP-Bang questionnaires and the Epworth sleepiness scale using polysomnography as gold standard.

作者信息

Godoy Paulo Henrique, Nucera Ana Paula Cassetta Dos Santos, Colcher Andressa de Paiva, de Andrade Jéssica Escorcio, Alves Davi da Silveira Barroso

机构信息

Federal University of the State of Rio de Janeiro, Sleep Laboratory of the Federal University of the State of Rio de Janeiro - LABSONO UNIRIO - Rio de Janeiro - Brazil.

Federal University of the State of Rio de Janeiro, Department of Quantitative Methods of the Federal University of the State of Rio de Janeiro - Rio de Janeiro - Brazil.

出版信息

Sleep Sci. 2022 Apr-Jun;15(2):136-142. doi: 10.5935/1984-0063.20220033.

DOI:10.5935/1984-0063.20220033
PMID:35755908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9210560/
Abstract

OBJECTIVES

Obstructive sleep apnea (OSA) affects approximately one third of the population and can reach 90% prevalence in the elderly. There are screening tools to track the disease, however, their performance may differ according to population characteristics. This study aims to determine sensitivity, specificity, predictive value, likelihood ratio, and accuracy of the Berlin (BQ) and STOP-Bang (S-Bang) questionnaires and the Epworth sleepiness scale (ESS), comparing their performances, using polysomnography (PSG) as a gold standard, in a sample of elderly.

MATERIAL AND METHODS

The study was cross-sectional, retrospective, included patients aged 60 or older who underwent PSG type 1, regardless of the BQ, S-Bang and ESS results, during the period of June 1, 2017 to April 30, 2019. OSA diagnosis was by PSG in which the hypopnea apnea index was greater than or equal to 5.

RESULTS

Sixty-two patients were evaluated; the prevalence of OSA was 72.58%. The mean age in the sample with OSA was 73.0±8.4 years and without it was 74.7±8.1 years. The sample was predominantly female, 58.1% with OSA. The BQ showed the best results for specificity, predictive value, likelihood ratio and accuracy. S-Bang had the best result for sensitivity and ESS showed the worst results. The BQ odds ratio showed that an individual with a positive BQ has 335% more chance of developing OSA.

CONCLUSION

The QB showed the best performance in the measures for identifying OSA, for a sample of elderly individuals, with a predominance of females and a high prevalence of the disease.

摘要

目的

阻塞性睡眠呼吸暂停(OSA)影响约三分之一的人口,在老年人中的患病率可达90%。有一些筛查工具可用于追踪该疾病,然而,其性能可能因人群特征而异。本研究旨在确定柏林问卷(BQ)、STOP-Bang问卷(S-Bang)和爱泼沃斯思睡量表(ESS)的敏感性、特异性、预测价值、似然比和准确性,以多导睡眠图(PSG)作为金标准,比较它们在老年样本中的性能。

材料与方法

本研究为横断面回顾性研究,纳入2017年6月1日至2019年4月30日期间接受1型PSG检查的60岁及以上患者,无论其BQ、S-Bang和ESS结果如何。OSA诊断采用PSG,其中呼吸暂停低通气指数大于或等于5。

结果

共评估了62例患者;OSA患病率为72.58%。OSA样本的平均年龄为73.0±8.4岁,无OSA样本的平均年龄为74.7±8.1岁。样本以女性为主,OSA患者中女性占58.1%。BQ在特异性、预测价值、似然比和准确性方面表现最佳。S-Bang的敏感性最佳,而ESS的结果最差。BQ比值比显示,BQ呈阳性的个体患OSA的可能性高出335%。

结论

对于以女性为主且疾病患病率高的老年样本,BQ在识别OSA的指标方面表现最佳。

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