Department of Polymer Materials, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
Key Scientific Research Base of Textile Conservation, State Administration for Cultural Heritage, China National Silk Museum, Hangzhou, 310002, China.
Mikrochim Acta. 2024 Nov 27;191(12):764. doi: 10.1007/s00604-024-06842-y.
A point-of-care testing (POCT) platform, i.e., a portable colorimetric immunosensor based on iron oxide magnetic beads and AuNPs, has been developed for detecting leather residues. The immunosensor demonstrates a linear detection range from 1 ng/mL to 10 µg/mL, with a limit of detection (LOD) of 0.985 ng/mL. The sensor exhibits high specificity and repeatability and performs effectively in detecting leather artifacts excavated from Inner Mongolia. Thus, the proposed colorimetric immunosensor not only enables the micro-detection of leather artifacts but also shows significant potential for on-site leather detection at archaeological sites.
一种即时检测（POCT）平台，即一种基于氧化铁磁珠和金纳米粒子的便携式比色免疫传感器，已被开发用于检测皮革残留物。该免疫传感器的检测范围从 1ng/mL 到 10μg/mL 呈线性，检测限（LOD）为 0.985ng/mL。该传感器表现出高特异性和重复性，并能有效地检测内蒙古出土的皮革制品。因此，所提出的比色免疫传感器不仅能够对皮革制品进行微量检测，而且在考古现场的现场皮革检测方面也显示出巨大的潜力。
