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糖尿病身体项目:针对1型糖尿病年轻女性的饮食失调预防计划的急性效应。一项跨国随机对照试验。

Diabetes Body Project: Acute Effects of an Eating Disorder Prevention Program for Young Women With Type 1 Diabetes. A Multinational Randomized Controlled Trial.

作者信息

Hennekes Mareille H C L, Haugvik Severina, de Wit Maartje, Toschi Elena, Desjardins Christopher D, Skrivarhaug Torild, Dahl-Jørgensen Knut, Stice Eric, Wisting Line

机构信息

Medical Psychology, Amsterdam UMC, Amsterdam, the Netherlands.

Amsterdam Public Health, Mental Health, Amsterdam, the Netherlands.

出版信息

Diabetes Care. 2025 Feb 1;48(2):220-225. doi: 10.2337/dc24-1599.

DOI:10.2337/dc24-1599
PMID:39602474
Abstract

OBJECTIVE

Young women with type 1 diabetes are at risk to develop eating disorders (ED). We evaluated a novel ED prevention program in a multinational randomized controlled trial.

RESEARCH DESIGN AND METHODS

Women (14-35 years old) with type 1 diabetes were randomized to virtual Diabetes Body Project groups or educational control. Outcomes were assessed at pretest and posttest (1-2 weeks after intervention).

RESULTS

Compared with educational controls (n = 146), participants in the Diabetes Body Project (n = 147) showed significant improvements (all P < 0.05), with small Cohen's d effect sizes for ED symptoms (d = -0.30, 95% CI -0.06, -0.69) (primary outcome), diabetes distress (d = -0.42), quality of life (d = 0.39) and dietary restraint (d = -0.31), and medium effect sizes for diabetes-specific disordered eating behaviors (d = -0.70), body dissatisfaction (d = -0.59), and pursuit of thin appearance ideal (d = -0.56).

CONCLUSIONS

The Diabetes Body Project produced significantly larger acute effects with small to medium effect sizes compared with educational controls and has potential for broad implementation.

摘要

目的

1型糖尿病年轻女性有患饮食失调症(ED)的风险。我们在一项多国随机对照试验中评估了一项新型的ED预防计划。

研究设计与方法

将1型糖尿病女性(14 - 35岁)随机分为虚拟糖尿病身体项目组或教育对照组。在干预前和干预后(干预后1 - 2周)评估结果。

结果

与教育对照组(n = 146)相比,糖尿病身体项目组(n = 147)的参与者有显著改善(所有P < 0.05),饮食失调症状(d = -0.30,95%CI -0.06,-0.69)(主要结局)、糖尿病困扰(d = -0.42)、生活质量(d = 0.39)和饮食限制(d = -0.31)的科恩d效应量较小,糖尿病特异性紊乱饮食行为(d = -0.70)、身体不满(d = -0.59)和追求瘦的外表理想(d = -0.56)的效应量为中等。

结论

与教育对照组相比,糖尿病身体项目产生了显著更大的急性效应,效应量小至中等,具有广泛实施的潜力。

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Diabet Med. 2025 Oct;42(10):e70108. doi: 10.1111/dme.70108. Epub 2025 Jul 25.