Characterizing molecular targets in difficult-to-treat rheumatoid arthritis.
作者信息
Smith Melanie H, Bai Zilong, Lakhanpal Amit, Ramirez Daniel, DiCarlo Edward, Donlin Laura, Orange Dana, Goodman Susan M
机构信息
Hospital for Special Surgery, New York, NY 10021, USA; Weill Cornell Medicine, New York, NY 10065, USA.
Weill Cornell Medicine, New York, NY 10065, USA.
出版信息
Semin Arthritis Rheum. 2025 Feb;70S:152588. doi: 10.1016/j.semarthrit.2024.152588. Epub 2024 Nov 19.
Abstract
摘要
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Sci Transl Med. 2024 Apr 10;16(742):eadk3506. doi: 10.1126/scitranslmed.adk3506.
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Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.类风湿关节炎滑膜的解构定义了炎症亚型。
Nature. 2023 Nov;623(7987):616-624. doi: 10.1038/s41586-023-06708-y. Epub 2023 Nov 8.
3
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial.利妥昔单抗与托珠单抗治疗类风湿关节炎：4 期 R4RA 随机试验基于滑膜活检的生物标志物分析。
Nat Med. 2022 Jun;28(6):1256-1268. doi: 10.1038/s41591-022-01789-0. Epub 2022 May 19.
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Persistent inflammatory and non-inflammatory mechanisms in refractory rheumatoid arthritis.难治性类风湿关节炎中的持续炎症和非炎症机制。
Nat Rev Rheumatol. 2021 Jan;17(1):17-33. doi: 10.1038/s41584-020-00541-7. Epub 2020 Dec 8.
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EULAR definition of difficult-to-treat rheumatoid arthritis.EULAR 定义的难治性类风湿关节炎。
Ann Rheum Dis. 2021 Jan;80(1):31-35. doi: 10.1136/annrheumdis-2020-217344. Epub 2020 Oct 1.
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A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients.少免疫滑膜型可预测类风湿关节炎患者对 TNFα 阻滞剂治疗反应不足。
Front Immunol. 2020 May 5;11:845. doi: 10.3389/fimmu.2020.00845. eCollection 2020.
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Cell Rep. 2019 Aug 27;28(9):2455-2470.e5. doi: 10.1016/j.celrep.2019.07.091.
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Arthritis Rheumatol. 2018 May;70(5):690-701. doi: 10.1002/art.40428. Epub 2018 Apr 2.
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