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生物型全髋关节置换联合打压植骨治疗类风湿关节炎继发中重度髋臼内陷

[Biological total hip arthroplasty combined with impacting bone grafting for the treatment of moderate to severe acetabular invagination secondary to rheumatoid arthritis].

作者信息

Liu Peng, Song Xiao-Yang, Chang Yan-Feng, Zhen Ping, Liu Jun, Zhou Sheng-Hu

机构信息

Department of Joint Surgery, the 940th Hospital of PLA Joint Logistics Support Force, Lanzhou 730050, Gansu, China.

Department of Orthopaedics, the Second Affiliated Hospital of Xi'an Jiaotong University, Northwest Hospital, Xi'an 710004, Shaanxi, China.

出版信息

Zhongguo Gu Shang. 2024 Nov 25;37(11):1087-95. doi: 10.12200/j.issn.1003-0034.20230068.

Abstract

OBJECTIVE

To explore the surgical technique and clinical outcomes of biological total hip arthroplasty(THA) combined with impacting bone grafting for the treatment of moderate to severe acetabular invagination secondary to rheumatoid arthritis(RA).

METHODS

Total of 20 patients(28 hips) with RA secondary to acetabular invagination were treated with THA of bioprosthesis combined with autogenous bone grafting from January 2012 to October 2020, including 5 males(8 hips) and 15 females(20 hips) with an average age of (55.10±4.96) years old from 45 to 64 years old. The depth of acetabular invagination was 8.43 to 16.25 mm with an average of (11.91±2.59) mm. According to Sotello-Garza and Charnley classification criterion, there were 15 cases(23 hips) of type Ⅱ(protrusio acetabuli 6 to 15 mm), and 5 cases(5 hips) of type Ⅲ(protrusio acetabuli>15 mm). Autologous femoral head granular bone and(or) allograft impacting grafting were used to reconstruct the acetabum, the biological porous acetabular cup was fixed by pressure fitting. At the postoperative follow-up, the activity function of the hip joint, the length of both lower limbs, VAS and Harris score were evaluated, and the healing of bone graft, the restoration of the hip rotation center and loosening of prosthesis were assessed by X-ray.

RESULTS

The operation time was 75 to 160 min with anverage of (103.32±18.18) min, the intraoperative blood loss was 150 to 650 ml with an average of (319.64±122.61) ml. There were no neurovascular complications during the operation. All patients were followed up from 2 to 10 years with an average of (5.45±2.50) years. The horizontal distance between the center of femoral head and the Kohler's line was increased from (11.40±1.85) mm preoperatively to (25.99±2.56) mm at the final follow-up(<0.01), and the vertical distance between the center of femoral head and the line joining bilateral ischial tuberosities was decreased from (89.36±5.20) mm preoperatively to (71.84±3.55) mm at the final follow-up(<0.01). The range of flexion motion of hip joint increased from (44.43±10.57)° preoperatively to (98.75±12.52)° at the final follow-up(<0.01), the range of abduction motion of hip joint increased from (12.50 ±6.01)°preoperatively to final follow-up (32.82±5.39)°(<0.01). The discrepancy of both lower limbs was significantly decreased from (19.39±5.93) mm preoperatively to (6.64±2.87) mm at the final follow-up(<0.01). The VAS decreased from (5.36±0.78) preoperatively to (1.82±0.86) at the final follow-up(<0.05), and the Harris score increased from (41.39±7.77) preoperatively to (89.00±4.67) at the final follow-up(<0.01). All the patients could move independently without assistance. Among them, 2 patients(2 hips) had hip pain after exercise, and 1 patient(1 hip) suffered from periprosthetic fracture due to fall.

CONCLUSION

Autologous femoral head granular bone grafting can reconstruct the acetabulum, and restore the rotation center of the hip joint, combined with biological porous tantalum/titanium acetabular cup can achieve good short-and medium-term outcomes in the treatment of moderate to severe acetabular invagination secondary to rheumatoid arthritis.

摘要

目的

探讨生物型全髋关节置换术(THA)联合打压植骨治疗类风湿关节炎(RA)继发中重度髋臼内陷的手术技术及临床疗效。

方法

2012年1月至2020年10月,对20例(28髋)RA继发髋臼内陷患者行生物型人工关节置换术联合自体骨移植治疗,其中男5例(8髋),女15例(20髋),年龄45~64岁,平均(55.10±4.96)岁。髋臼内陷深度8.43~16.25mm,平均(11.91±2.59)mm。根据Sotello-Garza和Charnley分类标准,Ⅱ型(髋臼突出6~15mm)15例(23髋),Ⅲ型(髋臼突出>15mm)5例(5髋)。采用自体股骨头颗粒骨和(或)同种异体骨打压植骨重建髋臼,生物型多孔髋臼杯压配固定。术后随访评估髋关节活动功能、双下肢长度、视觉模拟评分(VAS)和Harris评分,通过X线评估植骨愈合、髋关节旋转中心恢复及假体松动情况。

结果

手术时间75~160min,平均(103.32±18.18)min,术中出血量150~650ml,平均(319.64±122.61)ml。术中无神经血管并发症。所有患者随访2~10年,平均(5.45±2.50)年。末次随访时股骨头中心与科勒线的水平距离由术前(11.40±1.85)mm增加至(25.99±2.56)mm(P<0.01),股骨头中心与双侧坐骨结节连线的垂直距离由术前(89.36±5.20)mm降至(71.84±3.55)mm(P<0.01)。髋关节屈曲活动范围由术前(44.43±10.57)°增加至末次随访时(98.75±12.52)°(P<0.01),外展活动范围由术前(12.50±6.01)°增加至末次随访时(32.82±5.39)°(P<0.01)。双下肢长度差异由术前(19.39±5.93)mm显著降至末次随访时(6.64±2.87)mm(P<0.01)。VAS评分由术前(5.36±0.78)降至末次随访时(1.82±0.86)(P<0.05),Harris评分由术前(41.39±7.77)升至末次随访时(89.00±4.67)(P<0.01)。所有患者均能独立活动,无需辅助。其中2例(2髋)运动后髋关节疼痛,1例(1髋)因跌倒发生假体周围骨折。

结论

自体股骨头颗粒骨植骨可重建髋臼,恢复髋关节旋转中心,联合生物型多孔钽/钛髋臼杯治疗RA继发中重度髋臼内陷可获得良好的中短期疗效。

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