Hättasch Robert, Tscholl Verena, Hindricks Gerhard, Dagres Nikolaos
Klinik für Kardiologie, Angiologie, Intensivmedizin, Deutsches Herzzentrum der Charité, Campus Charité Mitte, Charitéplatz 1, 10117, Berlin, Deutschland.
Herz. 2025 Feb;50(1):3-7. doi: 10.1007/s00059-024-05287-6. Epub 2024 Nov 27.
The 2024 guidelines of the European Society of Cardiology (ESC) on atrial fibrillation (AF) present current and comprehensive recommendations for the diagnosis, prevention and treatment of AF. They are based on the AF-CARE treatment pathway, which includes modification of cardiovascular risk factors, stroke prevention, symptom management and continuous re-evaluation. Accordingly, all patients with newly diagnosed AF should undergo transthoracic echocardiography. Sodium-glucose cotransporter 2 (SGLT2) inhibitors are recommended for the treatment of heart failure across all clinical and echocardiographic levels of left ventricular ejection fraction (LVEF). The CHA2DS2-VASc score has been simplified to the CHA2DS2-VA score for the risk assessment of thromboembolism. For rate or rhythm control pharmacotherapy with beta-blockers, digitalis, amiodarone and flecainide are still the most important drugs. Pulmonary vein isolation is now also recommended as a first-line treatment for paroxysmal AF. Re-evaluation of risk factors and treatment of comorbidities is also emphasized. Overall the guidelines represent a further development and update based on recent studies. They remain practical and provide clear and detailed recommendations for action that are globally recognized in the clinical practice.
欧洲心脏病学会(ESC)2024年心房颤动(AF)指南针对房颤的诊断、预防和治疗提出了当前全面的建议。这些建议基于房颤护理治疗路径,该路径包括心血管危险因素的调整、中风预防、症状管理和持续重新评估。因此,所有新诊断为房颤的患者都应接受经胸超声心动图检查。对于所有临床和超声心动图左心室射血分数(LVEF)水平的心力衰竭患者,推荐使用钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂进行治疗。CHA2DS2-VASc评分已简化为CHA2DS2-VA评分,用于血栓栓塞的风险评估。对于使用β受体阻滞剂、洋地黄、胺碘酮和氟卡尼进行心率或节律控制的药物治疗,它们仍然是最重要的药物。肺静脉隔离现在也被推荐作为阵发性房颤的一线治疗方法。指南还强调了对危险因素的重新评估和合并症的治疗。总体而言,这些指南是基于近期研究的进一步发展和更新。它们仍然具有实用性,并为临床实践中全球公认的行动提供了清晰详细的建议。