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从果肉中提取的果胶样多糖:理化性质、抗氧化及皮肤保湿功效

Pectin-like polysaccharide extracted from pulp: physicochemical, antioxidant, and skin hydration efficacy.

作者信息

Sripisut Tawanun, Teja Aunchayakorn, Pengsuwan Naphaporn, Tree-Udom Thapakorn, Chanpirom Setinee

机构信息

School of Cosmetic Science, Mae Fah Luang University, Chiang Rai, Thailand.

Cosmetics for Beauty and Wellness Research Unit, Mae Fah Luang University, Chiang Rai, Thailand.

出版信息

Nat Prod Res. 2024 Nov 27:1-9. doi: 10.1080/14786419.2024.2434133.

Abstract

(currently accepted name of ) is a Cucurbitaceae vegetable with several biological activities. Polysaccharides from the fruit of were extracted and evaluated, producing a high extractive yield (17.20 ± 0.65%). The following physicochemical properties were provided: solubility and swelling capacity (99.51 ± 0.07% and 2.00 ± 0.00%, respectively), with a pH of 6.47 ± 0.02. The total polysaccharide content consisted of 0.23 ± 0.01 mg glucose/mg extract, while the total phenolic content was 19.99 ± 0.12 mg GAE/g extract, posing antioxidant activity on DPPH at IC of 214.38 ± 6.96 µg/mL. It was assumed from FT-IR that the extract consisted of pectin-like polysaccharides and other water-soluble polysaccharides. An study involving 20 volunteers showed that it did not cause skin irritation. A single application of the polysaccharide extract solutions (1.0 and 5.0% w/v) showed significantly greater short-term skin hydrating efficacy than the benchmark ( < 0.05), especially after 210 min, indicating its potential as a skin moisturising ingredient for cosmetics.

摘要

(当前公认名称)是一种具有多种生物活性的葫芦科蔬菜。从其果实中提取并评估了多糖,提取率较高(17.20 ± 0.65%)。给出了以下理化性质:溶解度和溶胀能力(分别为99.51 ± 0.07%和2.00 ± 0.00%),pH值为6.47 ± 0.02。总多糖含量为0.23 ± 0.01 mg葡萄糖/毫克提取物,而总酚含量为19.99 ± 0.12 mg没食子酸当量/克提取物,对DPPH的抗氧化活性IC为214.38 ± 6.96 µg/mL。通过傅里叶变换红外光谱推测提取物由果胶样多糖和其他水溶性多糖组成。一项涉及20名志愿者的研究表明它不会引起皮肤刺激。单次应用多糖提取物溶液(1.0和5.0% w/v)显示出比基准显著更高的短期皮肤保湿功效( < 0.05),尤其是在210分钟后,表明其作为化妆品皮肤保湿成分的潜力。

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