Wang Zhihai, Pan Min, Zeng Quan, Hu Guohua
Department of Otorhinolaryngology,the First Affiliated Hospital of Chongqing Medical University,Chongqing,400016,China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Dec;38(12):1190-1194;1202. doi: 10.13201/j.issn.2096-7993.2024.12.020.
The extranodal extension(ENE) is widely found in head and neck squamous cell carcinoma(HNSCC), which displays the aggressiveness of the tumor and increasing the risk of local recurrence and distant metastasis, so the ENE often has been used as an important indicator of prognosis and treatment. Although the pathologic and radiologic tests are currently the main diagnostic techniques for ENE, there is still a lack of uniform standards. The article reviews the prognostic value, pathologic and radiologic diagnosis of ENE in HNSCC over the recent years.
结外侵犯(ENE)在头颈部鳞状细胞癌(HNSCC)中广泛存在,它显示出肿瘤的侵袭性,并增加局部复发和远处转移的风险,因此ENE常被用作预后和治疗的重要指标。尽管病理和影像学检查目前是ENE的主要诊断技术,但仍缺乏统一标准。本文综述了近年来ENE在HNSCC中的预后价值、病理及影像学诊断。