Eitenmüller J
Orthopade. 1986 Feb;15(1):30-5.
With reference to the chemical and crystallographic differences, the line is drawn against bone substitute material produced from biological material. Extensive animal experiments demonstrated the good healing properties when using calcium phosphate ceramics in bony defects. In the long term, there was more new bone formed after filling up the defect with calcium phosphate ceramics than when using autologous bone grafts. Clinically, there is an indication for using this material to fill up bone cysts and defects if there is enough time for biodegradation; in other cases, a mixture using an autologous spongoid graft is necessary.
考虑到化学和晶体学差异，人们对由生物材料制成的骨替代材料持反对态度。大量动物实验表明，在骨缺损中使用磷酸钙陶瓷时具有良好的愈合特性。从长远来看，用磷酸钙陶瓷填充缺损后形成的新骨比使用自体骨移植时更多。临床上，如果有足够的时间进行生物降解，有指征使用这种材料来填充骨囊肿和缺损；在其他情况下，则需要使用自体海绵状移植骨的混合物。
