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3D打印在糖尿病足溃疡治疗中的应用:现状与新见解

Application of 3D printing in the treatment of diabetic foot ulcers: current status and new insights.

作者信息

Li Xinrui, Ai Xin, Wang Bo, Luo Mengqian, Miyamoto Akira, Kuchay Mohammad Shafi, Feng Dechao, Zhang Chi

机构信息

Department of Rehabilitation, The Affiliated Hospital of Southwest Medical University, Luzhou, China.

Department of Nishikyushu University Faculty of Rehabilitation, Fukuoka, Japan.

出版信息

Front Bioeng Biotechnol. 2024 Nov 13;12:1475885. doi: 10.3389/fbioe.2024.1475885. eCollection 2024.

Abstract

BACKGROUND AND AIMS

Diabetic foot ulcers (DFUs) are a serious complication of diabetes mellitus (DM), affecting around 25% of individuals with DM. Primary treatment of a DFU involves wound off-loading, surgical debridement, dressings to provide a moist wound environment, vascular assessment, and appropriate antibiotics through a multidisciplinary approach. Three-dimensional (3D) printing technology is considered an innovative tool for the management of DFUs. The utilization of 3D printing technology in the treatment of DFU involves the modernization of traditional methods and the exploration of new techniques. This review discusses recent advancements in 3D printing technology for the application of DFU care, and the development of personalized interventions for the treatment of DFUs.

METHODS

We searched the electronic database for the years 2019-2024. Studies related to the use of 3D printing technology in Diabetic foot were included.

RESULTS

A total of 25 identified articles based on database search and citation network analysis. After removing duplicates, 18 articles remained, and three articles that did not meet the inclusion criteria were removed after reading the title/abstract. A total of 97 relevant articles were included during the reading of references. In total, 112 articles were included.

CONCLUSION

3D printing technology offers unparalleled advantages, particularly in the realm of personalized treatment. The amalgamation of traditional treatment methods with 3D printing has yielded favorable outcomes in decelerating the progression of DFUs and facilitating wound healing. However, there is a limited body of research regarding the utilization of 3D printing technology in the domain of DFUs.

摘要

背景与目的

糖尿病足溃疡(DFUs)是糖尿病(DM)的一种严重并发症,影响约25%的糖尿病患者。糖尿病足溃疡的主要治疗包括伤口减压、手术清创、提供湿润伤口环境的敷料、血管评估以及通过多学科方法使用适当的抗生素。三维(3D)打印技术被认为是糖尿病足溃疡管理的一种创新工具。3D打印技术在糖尿病足溃疡治疗中的应用涉及传统方法的现代化和新技术的探索。本综述讨论了3D打印技术在糖尿病足溃疡护理应用方面的最新进展,以及糖尿病足溃疡个性化治疗干预措施的发展。

方法

我们检索了2019 - 2024年的电子数据库。纳入了与3D打印技术在糖尿病足应用相关的研究。

结果

基于数据库搜索和引文网络分析共识别出25篇文章。去除重复项后,剩余18篇文章,阅读标题/摘要后又排除了3篇不符合纳入标准的文章。阅读参考文献期间共纳入97篇相关文章。总共纳入112篇文章。

结论

3D打印技术具有无与伦比的优势,特别是在个性化治疗领域。传统治疗方法与3D打印技术的融合在减缓糖尿病足溃疡进展和促进伤口愈合方面取得了良好效果。然而,关于3D打印技术在糖尿病足溃疡领域的应用研究有限。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0821/11598536/4547a2b479c2/fbioe-12-1475885-g001.jpg

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