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转移性神经内分泌肿瘤继发急性肠系膜缺血:病例分析及文献复习

Acute mesenteric ischemia secondary to metastatic neuroendocrine tumor: a case analysis and review of the literature.

作者信息

Swafford Emily P, Magge Deepa R

机构信息

Department of Surgery, Vanderbilt University Medical Center, 1211 Medical Center Drive, Nashville, TN 37232, United States.

出版信息

J Surg Case Rep. 2024 Nov 27;2024(11):rjae725. doi: 10.1093/jscr/rjae725. eCollection 2024 Nov.

DOI:10.1093/jscr/rjae725
PMID:39606039
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11601975/
Abstract

Neuroendocrine tumors (NETs) are notably rare and frequently arise from the gastrointestinal tract. Generally asymptomatic, NETs uncommonly result in acute abdominal pain. We present a case of known metastatic NET manifesting as acute-on-chronic mesenteric ischemia due to the involvement of the superior mesenteric artery (SMA) and vein (SMV). A 63-year-old female with metastatic NET presented with acute-onset abdominal pain. The patient was hemodynamically stable but uncomfortable appearing with significant pain. Imaging demonstrated decreased enhancement of several small bowel loops within the right lower quadrant concerning for bowel ischemia with a mesenteric mass encasing the SMA and SMV. Surgical intervention revealed a nonviable loop of small bowel. Second-look laparotomy was performed with viable remaining bowel, and an ileocolic anastomosis was successfully created. Acute-onset abdominal pain in a patient with NET warrants urgent. Mesenteric ischemia, while rare, should not be overlooked, as timely diagnosis and intervention are imperative.

摘要

神经内分泌肿瘤(NETs)极为罕见,常起源于胃肠道。NETs通常无症状,很少导致急性腹痛。我们报告一例已知的转移性NET,表现为由于肠系膜上动脉(SMA)和静脉(SMV)受累导致的慢性肠系膜缺血急性发作。一名患有转移性NET的63岁女性出现急性腹痛。患者血流动力学稳定,但因疼痛明显而显得不适。影像学检查显示右下腹几个小肠袢强化减弱,提示肠缺血,肠系膜有一肿块包绕SMA和SMV。手术干预发现一段小肠已无活力。二次剖腹探查发现剩余肠管存活,成功进行了回结肠吻合术。NET患者出现急性腹痛需要紧急处理。肠系膜缺血虽然罕见,但不应被忽视,因为及时诊断和干预至关重要。

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