School of BioSciences and Technology, Vellore Institute of Technology, Vellore, India.
VIT School of Agricultural Innovation and Advanced Learning, Vellore Institute of Technology, Vellore, India.
Front Public Health. 2024 Nov 13;12:1402421. doi: 10.3389/fpubh.2024.1402421. eCollection 2024.
Heavy metal toxicity is a serious threat to human health due to its bioaccumulation, biomagnification, and persistent nature in the environment including aquatic systems. In the recent past, heavy metal contamination in the environment has occurred due to various anthropogenic sources. The concentration of potentially toxic heavy metals was determined by Atomic Absorption Spectroscopy in Tilapia (), a highly farmed and consumed fish species in southern parts of India. The mean levels of Fe were found to be higher in major organs of the fish with the highest levels in liver (Mean 1554.4 ± 1708.7 mg/kg) and lowest in the muscles (Mean 130.757 ± 33.3 mg/kg). Correlation Matrix analysis revealed relationships between the occurrence of various heavy metals in different organs of fish and indicated similar origins and chemical properties. Target hazard quotient for Cd, Co, Pb, and Cr in the Liver, Co and Cr in the Gills, and Co in Muscle were > 1 for adults, which showed a significant health risk from the combined effects of these metals. The potential health risk to humans, according to the cancer risk (CR) assessment is attributed mainly to Cd and Cr levels. Overall, moderate fish consumption is advised to limit the bioaccumulation of heavy metals over prolonged exposure and associated health risks.
重金属毒性由于其在环境中的生物积累、生物放大和持久性，包括水生系统，对人类健康构成严重威胁。在过去的一段时间里，由于各种人为来源，环境中的重金属污染已经发生。通过原子吸收光谱法测定了罗非鱼（Tilapia）中的潜在有毒重金属浓度，罗非鱼是印度南部大量养殖和消费的鱼类。结果发现，铁的浓度在鱼类的主要器官中较高，肝脏中的含量最高（平均值为 1554.4 ± 1708.7mg/kg），肌肉中的含量最低（平均值为 130.757 ± 33.3mg/kg）。相关矩阵分析揭示了不同鱼类器官中各种重金属的发生情况之间的关系，并表明它们具有相似的来源和化学性质。肝脏中 Cd、Co、Pb 和 Cr，鳃中 Co 和 Cr，肌肉中 Co 的目标危害商数（THQ）对于成年人来说均>1，这表明这些金属的联合作用对健康构成了重大风险。根据癌症风险（CR）评估，对人类的潜在健康风险主要归因于 Cd 和 Cr 水平。总体而言，建议适度食用鱼类，以限制长期暴露和相关健康风险导致的重金属生物积累。
