Snodgrass W R
Pediatr Clin North Am. 1986 Apr;33(2):381-91. doi: 10.1016/s0031-3955(16)35009-x.
Understanding of the pharmacologic principles and the pathogenesis of salicylate toxicity provides a basis for the optimization of clinical management. The role of salicylate as a scientifically proven cause of Reye's syndrome remains controversial despite epidemiologic data. The management guidelines discussed illustrate treatment details based on the pathophysiology of salicylate toxicity.