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展神经麻痹:不完全川崎病一种罕见的伴发体征。

Abducens nerve palsy: a rare copresenting sign of incomplete Kawasaki Disease.

作者信息

Lai Jennifer M, Milner Dallin C, Frisbie Ryan, Puente Michael A

机构信息

University of Colorado School of Medicine, Aurora, Colorado.

Department of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado; Department of Ophthalmology, Children's Hospital Colorado, Aurora, Colorado.

出版信息

J AAPOS. 2025 Feb;29(1):104061. doi: 10.1016/j.jaapos.2024.104061. Epub 2024 Nov 26.

Abstract

A 21-month-old girl presented with acute-onset esotropia with unexplained fever, conjunctivitis, and rash. Sensorimotor examination revealed the presence of a left abducens nerve palsy. After cardiogenic shock, she was found to have multiple large coronary artery aneurysms and was diagnosed with incomplete Kawasaki disease. The patient eventually had near-resolution of her abducens nerve palsy with treatment for her underlying Kawasaki disease through aspirin, infliximab, and intravenous immunoglobulin therapy. Abducens nerve palsy is a rare manifestation of Kawasaki disease that may reflect a late diagnosis and an increased risk of coronary artery involvement.

摘要

一名21个月大的女童出现急性内斜视,并伴有不明原因的发热、结膜炎和皮疹。感觉运动检查发现存在左侧外展神经麻痹。在心源性休克后,发现她有多个大型冠状动脉瘤,被诊断为不完全川崎病。通过阿司匹林、英夫利昔单抗和静脉注射免疫球蛋白治疗其潜在的川崎病后,该患者的外展神经麻痹最终几乎完全恢复。外展神经麻痹是川崎病的一种罕见表现,可能反映诊断较晚以及冠状动脉受累风险增加。

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