Division of Nephrology, Department of Internal Medicine, Van Yuzuncu Yil University Faculty of Medicine, Van, Turkey.
Division of Nephrology, Department of Internal Medicine, Bezmialem Vakif University School of Medicine, Istanbul, Turkey.
Med Sci Monit. 2024 Nov 29;30:e946471. doi: 10.12659/MSM.946471.
BACKGROUND During the COVID-19 pandemic, strict feeding restrictions were implemented in many dialysis centers to minimize transmission between patients. This study aims to evaluate the effects of these feeding restrictions on dry weight, intradialytic hypotension (IDH), and dialysis adequacy in hemodialysis patients. MATERIAL AND METHODS In this retrospective single-center study involving 76 hemodialysis patients, data from 2 consecutive 6-month periods were analyzed: the first before the COVID-19 pandemic when intradialytic nutrition was supported, and the second during the pandemic when intradialytic nutrition was restricted. Data from the patients' monthly visits during both periods were evaluated, averages were recorded, and a comparison was made between the 2 periods. RESULTS The frequency of IDH was significantly higher during the feeding period compared with the no-feeding period (1.4±1.2/month vs 0.81±0.86/month, P=0.01). Conversely, the urea reduction ratio was greater in the no-feeding period [72.5% (69-76) vs 71% (68-75), P=0.01], as were the single-pool Kt/V values (1.59±0.23 vs 1.52±0.26, P=0.004) and ultrafiltration rates (mL/h/kg) (11.4±3.0 vs 10.4±3.2, P=0.01). However, the dry weight of the patients was similar in the 2 periods (65.4±13.7 kg vs 65.7±14.2 kg, P=0.62). CONCLUSIONS During the COVID-19 pandemic, mandatory feeding restrictions for hemodialysis patients, aimed at reducing transmission, were linked to a decrease in IDH frequency and improved dialysis adequacy. However, no significant reduction in patients' dry weights was observed.
在 COVID-19 大流行期间，许多透析中心实施了严格的喂养限制，以最大程度地减少患者之间的传播。本研究旨在评估这些喂养限制对血液透析患者干体重、透析中低血压（IDH）和透析充分性的影响。
这是一项回顾性单中心研究，共纳入 76 名血液透析患者，分析了连续两个 6 个月的时期的数据：第一个时期是 COVID-19 大流行之前，支持透析中营养；第二个时期是大流行期间，限制透析中营养。评估了两个时期患者每月就诊的数据，记录平均值，并对两个时期进行了比较。
在喂养期间，IDH 的发生频率明显高于无喂养期间（1.4±1.2/月 vs 0.81±0.86/月，P=0.01）。相反，无喂养期间的尿素降低率更高[72.5%（69-76）比 71%（68-75），P=0.01]，单池 Kt/V 值更高[1.59±0.23 比 1.52±0.26，P=0.004]，超滤率更高（mL/h/kg）[11.4±3.0 比 10.4±3.2，P=0.01]。然而，两个时期患者的干体重相似[65.4±13.7 kg 比 65.7±14.2 kg，P=0.62]。
在 COVID-19 大流行期间，为了减少传播，对血液透析患者实施强制性喂养限制与 IDH 频率降低和透析充分性提高有关。然而，患者的干体重没有明显减轻。
