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全胃切除术后空肠瓣插入术治疗家族性腺瘤性息肉病患者:单中心经验报告

Jejunal flap interposition after total gastrectomy in managing patients with familial adenomatous polyposis: A report on the experience of a single centre.

作者信息

Barbosa José, Lopes Vítor, Sousa Fabiana, Baptista Manuela, Barbosa José Pedro, Barbosa Elisabete

机构信息

Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.

Department of General Surgery, São João University Hospital Center, Porto, Portugal.

出版信息

J Minim Access Surg. 2025 Jan 1;21(1):7-10. doi: 10.4103/jmas.jmas_161_23. Epub 2024 Nov 29.

Abstract

INTRODUCTION

Patients with familial adenomatous polyposis (FAP) are characterised by the appearance of colorectal cancer if the disease is left to follow its natural course, which means they frequently undergo prophylactic colectomy at a young age. In these patients, duodenal cancer becomes the leading cause of death, which deems surveillance necessary. Gastric cancer, although rare, can also occur in these patients, and total gastrectomy is the usual treatment option.

PATIENTS AND METHODS

We used a pedicled isoperistaltic jejunal flap interposition technique to reconstruct the digestive tract after a total gastrectomy so that duodenal surveillance could be maintained in patients followed in outpatient consultation for genetic diseases. We also describe how this technique was performed fully through laparoscopy in two of these cases.

RESULTS

We identified four patients with FAP who developed malignant or extensive pre-malignant gastric lesions which were not endoscopically resectable. Two patients were submitted to open surgery and the remaining two underwent laparoscopic surgery. There was no perioperative or post-operative morbidity, and all four patients are alive at the time of writing, with a minimum follow-up of 12 months. They were not diagnosed with major nutritional imbalances and were routinely submitted to endoscopic duodenal surveillance, sometimes including polypectomy, with ease.

CONCLUSION

In our experience, this surgical technique has good results, and all surgical steps can be done entirely through laparoscopy, with every advantage this approach entails.

摘要

引言

家族性腺瘤性息肉病(FAP)患者的特点是,如果疾病任其自然发展,就会出现结直肠癌,这意味着他们经常在年轻时接受预防性结肠切除术。在这些患者中,十二指肠癌成为主要死因,这使得监测变得必要。胃癌虽然罕见,但也可能发生在这些患者中,全胃切除术是通常的治疗选择。

患者与方法

我们采用带蒂顺蠕动空肠瓣插入技术在全胃切除术后重建消化道,以便在门诊咨询遗传性疾病的患者中维持十二指肠监测。我们还描述了在其中两例病例中如何通过腹腔镜完全实施该技术。

结果

我们确定了4例FAP患者,他们出现了恶性或广泛的癌前胃部病变,无法通过内镜切除。2例患者接受了开放手术,其余2例接受了腹腔镜手术。围手术期和术后均无并发症,在撰写本文时,所有4例患者均存活,最短随访时间为12个月。他们未被诊断出有严重的营养失衡,并且能够轻松地定期接受十二指肠内镜监测,有时还包括息肉切除术。

结论

根据我们的经验,这种手术技术效果良好,所有手术步骤都可以完全通过腹腔镜完成,具有这种方法所带来的各种优势。

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Gastric tumours in FAP.家族性腺瘤性息肉病中的胃肿瘤
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