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家族性腺瘤性息肉病的发病率。丹麦息肉病登记处的结果。

The incidence rate of familial adenomatous polyposis. Results from the Danish Polyposis Register.

作者信息

Bülow S, Faurschou Nielsen T, Bülow C, Bisgaard M L, Karlsen L, Moesgaard F

机构信息

Danish Polyposis Register, Department of Surgical Gastroenterology, Hvidvore Hospital, University of Copenhagen, Hvidovre, Denmark.

出版信息

Int J Colorectal Dis. 1996;11(2):88-91. doi: 10.1007/BF00342466.

DOI:10.1007/BF00342466
PMID:8739833
Abstract

Based on the Danish Polyposis Register epidemiological calculations on familial adenomatous polyposis (FAP) were carried out. The mean annual incidence was 1.85 x 10(-6) during the years 1971-1992, and the prevalence increasing to about 32 x 10(-6) at the end of 1992. FAP patients constituted a decreased percentage of all Danish patients with colorectal cancer (0.07% in 1980-1992). The completeness of registration was 97% in 1983-1992. The results are similar to Finnish estimates based on the same direct method of calculation, and as both series are based on almost complete national polyposis registration in well-registered populations we regard our results to be close to the true incidence rate.

摘要

基于丹麦息肉病登记处的数据,对家族性腺瘤性息肉病(FAP)进行了流行病学计算。1971年至1992年期间,年平均发病率为1.85×10⁻⁶,到1992年底患病率增至约32×10⁻⁶。FAP患者在所有丹麦结直肠癌患者中所占比例下降(1980 - 1992年为0.07%)。1983年至1992年登记的完整性为97%。这些结果与芬兰基于相同直接计算方法的估计结果相似,并且由于这两个系列均基于登记良好人群中几乎完整的全国息肉病登记数据,我们认为我们的结果接近真实发病率。

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A genetic study of multiple polyposis of the colon with an appendix deriving a method of estimating relative fitness.一项关于伴有阑尾的结肠多发性息肉病的遗传学研究,推导一种估计相对适合度的方法。
Am J Hum Genet. 1955 Sep;7(3):236-63.
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Centralized registration, prophylactic examination, and treatment results in improved prognosis in familial adenomatous polyposis. Results from the Danish Polyposis Register.集中登记、预防性检查和治疗可改善家族性腺瘤性息肉病的预后。丹麦息肉病登记处的结果。
Scand J Gastroenterol. 1995 Oct;30(10):989-93. doi: 10.3109/00365529509096343.
3
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Establishing a Genetic Cancer Risk Assessment Clinic.建立一个遗传性癌症风险评估诊所。
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