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实施紧急剖宫产政策及其对阿卜杜勒阿齐兹国王大学医院母婴结局的影响:一项回顾性研究。

Implementation of a crash cesarean section policy and its impact on maternal and neonatal outcomes at King Abdulaziz University Hospital: A retrospective study.

机构信息

Department of Obstetrics and Gynecology, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

出版信息

Medicine (Baltimore). 2024 Nov 29;103(48):e40645. doi: 10.1097/MD.0000000000040645.

Abstract

A typical surgical technique for pregnant women with potentially fatal problems affecting the mother or fetus is an emergency cesarean section (ECS). The decision-to-delivery interval (DDI) for ECS should be within 30 minutes. The objective of this study was to investigate crash ECS indications and effects on maternal and neonatal outcomes. In this retrospective study, all women undergoing crash cesarean section (CS) at Obstetrics and Gynecology department at King Abdulaziz University hospital, Jeddah, Saudi Arabia during 2022 and 2023 were evaluated. Data about demographic and obstetric characteristics of mother, ECS indications, DDI, and outcomes for mothers and newborns was gathered from the patient's sheet. One hundred 3 crash CS were performed during study period. Crash CS indications were fetal bradycardia (64.1%), prolapsed cord (24.3%), uterine rupture (6.8%), and severe antepartum hemorrhage (4.9%). D-D time range from 2 to 30 minutes. DDI was ≤15 minutes in 90 patients (87.4%) and >15 minutes in 13 patients (12.6%). Gestational age was <32 weeks (16.7%), between 32 and <37 weeks (15.5%), and ≥37 weeks (68.0%). Good maternal outcome was reported in 89 (86.4%), while 24 (13.6%) had complications. Intensive care unit maternal admission was significantly higher in gestational age 32 to <37 weeks versus <32 weeks and ≥37 weeks of gestation (18.8% vs 5.9% and 2.9%, P = .050). Fetal outcome was good in 69 (67.0%), while 34 (33.0%) had complications. Neonatal body weights, Apgar score at 1, 5, 10 minutes, and umbilical cord arterial pH were significantly decreased in preterm versus termed neonates (P < .0001, P < .0001, P < .0001, P = .014, and P = .003). Moreover, respiratory distress syndrome, jaundice, intubation, neonatal deaths, and sepsis were significantly higher in preterm versus term deliveries (P < .0001, P = .029, P < .0001, P = .010, and P = .031). Good neonatal outcome was significantly higher (P < .0001); while respiratory distress syndrome was significantly lower (P = .007) in deliveries with DDI ≤ 15 minutes versus > 15 minutes. The 30-minute standard for DDI time interval may be a feasible guideline at least for level-3 hospitals. Crash CS indication was mostly due to fetal bradycardia. The maternal and neonatal outcomes were better in term than preterm deliveries. The positive effect of very short intervals on neonatal outcome still needs to be proven.

摘要

一种用于治疗危及母亲或胎儿的潜在致命问题的孕妇的典型手术技术是紧急剖宫产术(ECS)。ECS 的决策-分娩间隔(DDI)应在 30 分钟内。本研究的目的是调查紧急剖宫产的指征及其对母婴结局的影响。在这项回顾性研究中,评估了 2022 年至 2023 年在沙特阿拉伯吉达阿卜杜勒阿齐兹国王大学医院妇产科接受紧急剖宫产的所有女性。从患者病历中收集了母亲的人口统计学和产科特征、剖宫产指征、DDI 以及母婴结局的数据。研究期间共进行了 100 次紧急剖宫产。紧急剖宫产的指征为胎儿心动过缓(64.1%)、脐带脱垂(24.3%)、子宫破裂(6.8%)和严重产前出血(4.9%)。DD 时间范围为 2 至 30 分钟。90 例患者的 DDI 时间≤15 分钟(87.4%),13 例患者的 DDI 时间>15 分钟(12.6%)。胎龄<32 周(16.7%)、32-<37 周(15.5%)和≥37 周(68.0%)。89 例(86.4%)产妇结局良好,24 例(13.6%)有并发症。与胎龄<32 周和≥37 周的产妇相比,胎龄 32-<37 周的产妇需要入住重症监护病房的比例显著更高(18.8%比 5.9%和 2.9%,P=0.050)。69 例(67.0%)胎儿结局良好,34 例(33.0%)有并发症。与足月新生儿相比,早产儿的新生儿体重、1 分钟、5 分钟和 10 分钟时的 Apgar 评分以及脐动脉 pH 值显著降低(P<0.0001、P<0.0001、P<0.0001、P=0.014 和 P=0.003)。此外,与足月分娩相比,早产儿发生呼吸窘迫综合征、黄疸、插管、新生儿死亡和败血症的比例显著更高(P<0.0001、P=0.029、P<0.0001、P=0.010 和 P=0.031)。DDI 时间间隔≤15 分钟的分娩新生儿结局良好的比例显著更高(P<0.0001),而呼吸窘迫综合征的比例显著更低(P=0.007)。30 分钟的 DDI 时间间隔标准至少对 3 级医院来说可能是一个可行的指南。紧急剖宫产的指征主要是胎儿心动过缓。与早产儿相比,足月分娩的母婴结局更好。非常短的间隔对新生儿结局的积极影响仍有待证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/11608669/ab3b8d4bfa10/medi-103-e40645-g001.jpg

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