Koc Samed, Cengiz Aysegul, Polat Burak, Kahraman Kokten Sevval, Gultekin Zeynep Nur, Caliskan Cansu, Tufan-Cetin Ozge, Cetin Huseyin
Laboratory Animals Application and Research Centre, Akdeniz University, Antalya, Türkiye.
Faculty of Science, Department of Biology, Akdeniz University, Antalya, Türkiye.
Vet Parasitol. 2025 Jan;333:110361. doi: 10.1016/j.vetpar.2024.110361. Epub 2024 Nov 28.
This research aims to investigate the repellent effects of five major components of plant essential oils (carvacrol, geraniol, cineole, α-pinene, and γ-terpinene) on the brown dog tick, Rhipicephalus sanguineus sensu lato (Acari: Ixodidae), using the newly developed Larval Repellent Activity Test (LRAT). The components were tested at concentrations of 0.1 %, 0.5 %, 1 %, 2.5 %, and 5 %, with DEET as a positive control. Carvacrol and geraniol exhibited strong repellent effects, with carvacrol showing efficacy comparable to DEET (15 %) at certain concentrations and time points. In contrast, cineole, γ-terpinene, and α-pinene demonstrated moderate to low repellency. The results highlight the potential of using plant-derived components as safer alternatives to synthetic repellents, suggesting that these natural compounds could be developed into effective biocidal products for tick control.
本研究旨在利用新开发的幼虫驱避活性试验（LRAT），研究植物精油的五种主要成分（香芹酚、香叶醇、桉叶素、α-蒎烯和γ-松油烯）对血红扇头蜱（Rhipicephalus sanguineus sensu lato，蜱螨目：硬蜱科）的驱避效果。以避蚊胺作为阳性对照，对这些成分在0.1%、0.5%、1%、2.5%和5%的浓度下进行了测试。香芹酚和香叶醇表现出强烈的驱避效果，香芹酚在某些浓度和时间点的效果与避蚊胺（15%）相当。相比之下，桉叶素、γ-松油烯和α-蒎烯表现出中度至低度的驱避性。结果突出了使用植物源成分作为合成驱避剂更安全替代品的潜力，表明这些天然化合物可开发成有效的杀蜱生物产品。
