Marcellou Effimia G, Stasi Sophia, Giannopapas Vasileios, Bø Kari, Bakalidou Daphne, Konstadoulakis Manousos, Papathanasiou George
Laboratory of Neuromuscular and Cardiovascular Study of Motion (LANECASM), Physiotherapy Department, University of West Attica (UNIWA), Athens, Greece.
Laboratory of Neuromuscular and Cardiovascular Study of Motion (LANECASM), Physiotherapy Department, University of West Attica (UNIWA), Athens, Greece.
Eur J Obstet Gynecol Reprod Biol. 2025 Jan;304:134-140. doi: 10.1016/j.ejogrb.2024.11.040. Epub 2024 Nov 26.
Urinary incontinence (UI) is common in women of all age groups, but postmenopausal women (MW) have a higher incidence of these symptoms. The International Continence Society suggests that women with UI should first try a conservative treatment, such as pelvic floor muscle training (PFMT), which aims to enhance the strength and rectify the activation patterns of the pelvic floor muscles. The aim of this study was to examine the effectiveness of PFMT, either on its own, or in conjunction with other physical therapy, in reducing the severity of UI symptoms in MW.
A comprehensive literature search was performed to identify relevant publications from major medical databases. A meta-analysis was carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) model. In addition, the included studies were assessed for quality, heterogeneity and publication bias.
After screening, application of the inclusion/exclusion criteria, and bias assessment, five randomized controlled trials were evaluated. PFMT was found to have a significant and substantial impact on the level of UI in the total patient population (standardized mean difference between the intervention and control groups -1.30, 95%CI: -1.97, -0.62, p ≤ 0.01, I = 88.5 %; probability of benefit = 0.92). A second analysis, after the removal of studies that combined PFMT with electrostimulation or biofeedback, returned similar results.
PFMT is an effective intervention for the management of UI in MW. Our analysis shows a 92% chance of significant improvement for patients receiving PFMT in comparison with controls. Future studies should examine its efficacy in MW subgroups with symptoms of genitourinary syndrome of menopause (GSM).
尿失禁在各年龄段女性中均很常见,但绝经后女性这些症状的发生率更高。国际尿控协会建议,尿失禁女性应首先尝试保守治疗,如盆底肌训练(PFMT),其目的是增强盆底肌力量并纠正其激活模式。本研究的目的是检验PFMT单独使用或与其他物理治疗联合使用时,在减轻绝经后女性尿失禁症状严重程度方面的有效性。
进行全面的文献检索,以确定来自主要医学数据库的相关出版物。根据系统评价和Meta分析的首选报告项目(PRISMA)模型进行Meta分析。此外,对纳入的研究进行质量、异质性和发表偏倚评估。
经过筛选、应用纳入/排除标准和偏倚评估,对五项随机对照试验进行了评估。发现PFMT对全部患者人群的尿失禁水平有显著且实质性的影响(干预组与对照组之间的标准化均值差为-1.30,95%CI:-1.97,-0.62,p≤0.01,I=88.5%;获益概率=0.92)。在剔除将PFMT与电刺激或生物反馈相结合的研究后进行的第二项分析得出了类似结果。
PFMT是治疗绝经后女性尿失禁的有效干预措施。我们的分析表明,与对照组相比,接受PFMT治疗的患者有92%的机会得到显著改善。未来的研究应检验其在有绝经泌尿生殖综合征(GSM)症状的绝经后女性亚组中的疗效。