Klein B, Falkson G, Terblanche A P, Klein T, Potgieter H C, Smit C F
S Afr Med J. 1986 Mar 1;69(5):283-6.
An analysis of prognostic factors for predicting time to treatment failure (TTF) was performed on 246 patients who were referred for adjuvant chemotherapy after mastectomy. Oestrogen receptor (ER) and progesterone receptor (PgR) analyses were carried out on 172 and 102 patients respectively. Prognostic factors predicting for TTF were, in decreasing order of significance: nodal status, tumour size, ER status and age of the patient. Comparison of TTF for ER+ and ER- (without categories of other prognostic factors) showed that ER status is prognostic irrespective of nodal status. ER is prognostically significant within both categories of PgR. PgR predicted significantly for TTF only in patients without nodal involvement.
对246例乳房切除术后接受辅助化疗的患者进行了预测治疗失败时间（TTF）的预后因素分析。分别对172例和102例患者进行了雌激素受体（ER）和孕激素受体（PgR）分析。预测TTF的预后因素按重要性降序排列为：淋巴结状态、肿瘤大小、ER状态和患者年龄。比较ER阳性和ER阴性患者的TTF（不考虑其他预后因素类别）显示，无论淋巴结状态如何，ER状态都具有预后意义。在PgR的两类患者中，ER在预后方面都具有显著意义。PgR仅在无淋巴结受累的患者中对TTF有显著预测作用。
