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老年肝内胆管结石和/或胆总管结石患者腹腔镜胆总管探查术后一期缝合与T管引流的比较:一项倾向评分匹配的对照研究

Primary closure compared with T-tube drainage following laparoscopic common bile duct exploration among elderly patients with hepatolithiasis and/or choledocholithiasis: a comparative study using a propensity score matching.

作者信息

La Phu V, Le Hieu T, Tran Thang M, Tran Quan M, La Phuc V, Doan Vu A

机构信息

General Surgery Department, Can Tho General Hospital, Can Tho, Viet Nam.

Human Organ and Tissue Transplant Center, 108 Military Central Hospital, Hanoi, Viet Nam.

出版信息

HPB (Oxford). 2025 Feb;27(2):232-239. doi: 10.1016/j.hpb.2024.11.004. Epub 2024 Nov 20.


DOI:10.1016/j.hpb.2024.11.004
PMID:39616106
Abstract

BACKGROUND: Laparoscopic common bile duct exploration (LCBDE) is commonly used for hepatolithiasis and/or choledocholithiasis, but the ideal method for common bile duct closure remains uncertain, especially for elderly patients (≥65 years). This study compared outcomes of primary closure versus T-tube drainage following LCBDE in elderly patients. METHODS: Data from elderly patients undergoing LCBDE for hepatolithiasis and/or choledocholithiasis between May 2016 and December 2020 at two Vietnamese hospitals were analyzed. Patients were divided into groups A (T-tube drainage, n = 52) and B (primary closure, n = 57). Propensity score matching (PSM) was utilized to adjust for baseline characteristics, comparing short- and long-term outcomes between groups. RESULTS: PSM yielded 56 matched patients. Pre-PSM, group A had longer operating times and hospital stays than Group B (p = 0.001). Group A had higher postoperative complications (17.9 % vs. 7.1 %) but was not statistically significant (p = 0.422). Group A also had more complex biliary stones. Post-PSM, Group B maintained shorter operating times and hospital stays. Regarding long-term results, stone recurrence rates were similar (5.8 % vs. 3.5 %, p = 0.668). CONCLUSION: Primary closure following LCBDE is a safe and effective alternative to T-tube drainage for treating hepatolithiasis and/or choledocholithiasis in elderly patients.

摘要

背景:腹腔镜胆总管探查术(LCBDE)常用于肝内胆管结石和/或胆总管结石,但胆总管闭合的理想方法仍不确定,尤其是对于老年患者(≥65岁)。本研究比较了老年患者LCBDE术后一期缝合与T管引流的效果。 方法:分析了2016年5月至2020年12月期间在两家越南医院接受LCBDE治疗肝内胆管结石和/或胆总管结石的老年患者的数据。患者分为A组(T管引流,n = 52)和B组(一期缝合,n = 57)。采用倾向评分匹配(PSM)来调整基线特征,比较两组的短期和长期结果。 结果:PSM产生了56例匹配患者。在PSM之前,A组的手术时间和住院时间比B组长(p = 0.001)。A组术后并发症发生率较高(17.9%对7.1%),但无统计学意义(p = 0.422)。A组的胆管结石也更复杂。PSM后,B组的手术时间和住院时间仍较短。关于长期结果,结石复发率相似(5.8%对3.5%,p = 0.668)。 结论:对于老年患者肝内胆管结石和/或胆总管结石的治疗,LCBDE术后一期缝合是一种安全有效的替代T管引流的方法。

相似文献

[1]
Primary closure compared with T-tube drainage following laparoscopic common bile duct exploration among elderly patients with hepatolithiasis and/or choledocholithiasis: a comparative study using a propensity score matching.

HPB (Oxford). 2025-2

[2]
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Surg Endosc. 2025-4

[3]
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[4]
Laparoscopic common bile duct exploration with primary closure for management of choledocholithiasis: a retrospective analysis and comparison with conventional T-tube drainage.

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[5]
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[6]
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[7]
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[8]
Systematic review with meta-analysis of studies comparing primary duct closure and T-tube drainage after laparoscopic common bile duct exploration for choledocholithiasis.

Surg Endosc. 2016-3

[9]
T-tube drainage versus primary closure after laparoscopic common bile duct exploration.

Cochrane Database Syst Rev. 2013-6-21

[10]
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Asian J Surg. 2023-8

引用本文的文献

[1]
Common bile duct exploration with choledochotomy and primary repair during pregnancy: Case Report.

Front Med (Lausanne). 2025-4-15

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