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利用静态站立平衡识别帕金森病及其阶段。

Identifying Parkinson's disease and its stages using static standing balance.

作者信息

Jung Dawoon, Yoo Dallah, Kim Jinwook, Ahn Tae-Beom, Mun Kyung-Ryoul

机构信息

Center for Intelligence and Interaction Research, Korea Institute of Science and Technology, Seoul, Republic of Korea.

Department of Neurology, Kyung Hee University Hospital, Kyung Hee University College of Medicine, Seoul, Republic of Korea.

出版信息

NPJ Digit Med. 2024 Nov 30;7(1):347. doi: 10.1038/s41746-024-01351-x.

Abstract

The current assessment of Parkinson's disease (PD) relies on dynamic motor tasks, limiting accessibility. This study aimed to propose an innovative approach to identifying PD and its stages using static standing balance and machine learning. A total of 210 participants were recruited, including a control group and five PD groups categorized by stage. Each participant completed a 10-s static standing balance task in which center of pressure trajectory data in the medial-lateral and anterior-posterior directions were collected. Features were extracted from these trajectory data and the data derived from them using both representation learning and handcrafting methods. A Transformer encoder-based classifier was trained on these features and achieved an F-score of 0.963 in classifying the six study groups. This approach enhances the accessibility of PD assessment, enabling earlier detection and timely intervention. The novel data mining framework introduced in this study heralds a new era of time-series data-driven digital healthcare.

摘要

目前对帕金森病(PD)的评估依赖于动态运动任务,这限制了其可及性。本研究旨在提出一种创新方法,利用静态站立平衡和机器学习来识别帕金森病及其阶段。共招募了210名参与者,包括一个对照组和按阶段分类的五个帕金森病组。每位参与者完成了一项10秒的静态站立平衡任务,在此过程中收集了压力中心轨迹在内侧-外侧和前后方向上的数据。使用表征学习和手工制作方法从这些轨迹数据及其衍生数据中提取特征。基于Transformer编码器的分类器在这些特征上进行训练,并在对六个研究组进行分类时获得了0.963的F分数。这种方法提高了帕金森病评估的可及性,能够实现早期检测和及时干预。本研究中引入的新型数据挖掘框架预示着时间序列数据驱动的数字医疗新时代的到来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e3d/11608222/d4e4fe502b34/41746_2024_1351_Fig1_HTML.jpg

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