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成人肠内营养不耐受的风险预测模型——文献综述

Risk prediction model for adult intolerance to enteral nutrition feeding - A literature review.

作者信息

Yang Hui, Liu Jinmei, Sun Hongyan

机构信息

School of Nursing, Southwest Medical University, Luzhou, Sichuan 646000, China; The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan 610500, China.

The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan 610500, China.

出版信息

Am J Med Sci. 2025 Apr;369(4):427-433. doi: 10.1016/j.amjms.2024.11.012. Epub 2024 Nov 30.

Abstract

Enteral nutrition is an important clinical nutritional supplementation method, especially for adult patients who are unable to eat normally or require additional nutritional support. However, many patients experience intolerance to enteral nutrition, such as delayed gastric emptying, bloating, and diarrhea, which not only affect the patient's nutritional status but also increase the risk of medical complications. In recent years, medical researchers have been dedicated to identifying and analyzing various factors that contribute to enteral nutrition intolerance, including the patient's disease status, nutritional formula, feeding method, and rate. In addition, research is also exploring the establishment of risk prediction models to more accurately predict which patients may develop enteral nutrition intolerance. These models typically combine clinical parameters, biomarkers, and patient individual characteristics, aiming to assist clinicians in better planning and adjusting nutritional treatment plans, thereby reducing the occurrence of intolerance events. This review summarizes the research progress on enteral nutrition intolerance in adult patients, with a focus on the latest developments in intolerance factors and risk prediction models, providing valuable guidance for clinical practice and helping improve patients' nutritional status and overall health.

摘要

肠内营养是一种重要的临床营养补充方法,尤其适用于无法正常进食或需要额外营养支持的成年患者。然而,许多患者会出现肠内营养不耐受,如胃排空延迟、腹胀和腹泻,这不仅会影响患者的营养状况,还会增加医疗并发症的风险。近年来,医学研究人员一直致力于识别和分析导致肠内营养不耐受的各种因素,包括患者的疾病状态、营养配方、喂养方法和速度。此外,研究还在探索建立风险预测模型,以更准确地预测哪些患者可能发生肠内营养不耐受。这些模型通常结合临床参数、生物标志物和患者个体特征,旨在帮助临床医生更好地规划和调整营养治疗方案,从而减少不耐受事件的发生。本综述总结了成年患者肠内营养不耐受的研究进展,重点关注不耐受因素和风险预测模型的最新发展,为临床实践提供有价值的指导,并有助于改善患者的营养状况和整体健康。

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