Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Department of Pathology, Kindai University Faculty of Medicine, Japan.
Intern Med. 2024;63(23):3171-3178. doi: 10.2169/internalmedicine.3508-24. Epub 2024 Dec 1.
In November 2019, a 76-year-old woman was diagnosed with limited cutaneous scleroderma caused by Raynaud's phenomenon and skin hardening on the periphery of the extremities. In October 2022, blood tests and abdominal ultrasonography revealed liver dysfunction and multiple liver masses, respectively. In November 2022, a percutaneous liver mass biopsy revealed peliosis hepatitis, so the patient was referred to Kindai University Hospital, and signs of liver failure were observed. Considering her age, the patient was ineligible for liver transplantation, and she died in September 2023. Peliosis hepatis complicated by scleroderma has not been previously reported, so we report this as a valuable case.
2019 年 11 月,一位 76 岁女性被诊断为由雷诺现象引起的局限性硬皮病,四肢周围出现皮肤硬化。2022 年 10 月,血液检查和腹部超声检查分别显示肝功能异常和多个肝占位。2022 年 11 月,经皮肝肿块活检显示肝血窦扩张,因此患者被转介至近畿大学医院,观察到肝功能衰竭的迹象。考虑到她的年龄,患者不符合肝移植条件,于 2023 年 9 月死亡。硬皮病并发肝血窦扩张此前未有报道,因此我们将其作为一个有价值的病例报告。