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伴有部分三倍体胎盘的二倍体胎儿:病例报告及处理策略

Diploid fetus with partially triploid placenta: case presentation and management strategy.

作者信息

Sahebdel Behrokh, Moghimi Zahra, Sobhanian Ehsan, Shirali Elham, Yarandi Fariba, Golshahi Fatemeh, Shirazi Mahboobeh, Saedi Nafiseh, Rashidi-Nezhad Ali

机构信息

Department of Obstetrics and Gynecology, Fellowship of Fetal-Maternal Medicine, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Department of Obstetrics and Gynecology, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Matern Health Neonatol Perinatol. 2024 Dec 2;10(1):24. doi: 10.1186/s40748-024-00195-3.

DOI:10.1186/s40748-024-00195-3
PMID:39617944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11610298/
Abstract

Multiple placental cysts are a common finding in obstetric ultrasound imaging. Although they have benign differential diagnoses, such as hydropic degeneration of the placenta or placental mesenchymal dysplasia, it's important to consider significant pathologies, such as benign gestational trophoblastic disease or hydatidiform mole. A challenging issue in obstetrics is pregnancies with a placenta that has a bipartite texture. This means that one side of the placenta is normal, but the other side is full of cystic formations, and only one fetus is visualized. The main critical concern is the presence of a molar pregnancy because of its catastrophic consequences. Here, we report a rare case in which the gravid uterus had a normal diploid fetus but had a bipartite placenta, which was triploid in the hydropic part, revealing a unique genetic pattern.

摘要

多发性胎盘囊肿是产科超声成像中的常见发现。尽管它们有良性鉴别诊断,如胎盘水肿变性或胎盘间质性发育异常,但考虑重要的病理情况,如良性妊娠滋养细胞疾病或葡萄胎,是很重要的。产科一个具有挑战性的问题是胎盘呈二分质地的妊娠。这意味着胎盘的一侧正常,但另一侧充满囊性结构,且仅可见一个胎儿。主要的关键问题是存在葡萄胎妊娠,因为其后果严重。在此,我们报告一例罕见病例,妊娠子宫内有一个正常的二倍体胎儿,但胎盘呈二分,水肿部分为三倍体,揭示了一种独特的基因模式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9190/11610298/e374f4477c94/40748_2024_195_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9190/11610298/64101cdcd6fe/40748_2024_195_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9190/11610298/068986fdc656/40748_2024_195_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9190/11610298/e374f4477c94/40748_2024_195_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9190/11610298/64101cdcd6fe/40748_2024_195_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9190/11610298/068986fdc656/40748_2024_195_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9190/11610298/e374f4477c94/40748_2024_195_Fig3_HTML.jpg

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Partial Molar Pregnancy With Normal Karyotype.核型正常的部分性葡萄胎
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Partial Hydatidiform Mole and Coexistent Live Fetus: A Case Report and Review of the Literature.部分性葡萄胎与并存活胎:一例报告及文献复习
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