Mittal Disha, Anand Rama, Sisodia Neha, Singh Smita, Biswas Ratna
Department of Radiodiagnosis, Lady Hardinge Medical College, New Delhi, India.
Indian J Radiol Imaging. 2017 Jan-Mar;27(1):62-64. doi: 10.4103/0971-3026.202949.
Placental mesenchymal dysplasia (PMD) is an uncommon vascular anomaly of the placenta characterized by placentomegaly with multicystic placental lesion on ultrasonography and mesenchymal stem villous hyperplasia on histopathology. Placental mesenchymal dysplasia should be considered in the differential diagnosis of cases of multicystic placental lesion such as molar pregnancy, chorioangioma, subchorionic hematoma, and spontaneous abortion with hydropic placental changes. However, lack of high-velocity signals inside the lesion and a normal karyotype favor a diagnosis of PMD. PMD must be differentiated from gestational trophoblastic disease because management and outcomes differ. We report the case of an 18-year-old female at 15 weeks of gestation with sonographic findings suggestive of placental mesenchymal dysplasia. The diagnosis was confirmed on histopathology.
胎盘间充质发育异常（PMD）是一种罕见的胎盘血管异常，其特征为超声检查显示胎盘肿大伴多囊性胎盘病变，组织病理学表现为间充质干细胞绒毛增生。在鉴别诊断多囊性胎盘病变时，如葡萄胎、绒毛膜血管瘤、绒毛膜下血肿以及伴有水肿性胎盘改变的自然流产等情况时，应考虑胎盘间充质发育异常。然而，病变内部缺乏高速血流信号以及核型正常有助于诊断PMD。由于治疗方法和预后不同，PMD必须与妊娠滋养细胞疾病相鉴别。我们报告一例妊娠15周的18岁女性病例，其超声检查结果提示胎盘间充质发育异常。组织病理学检查确诊了该诊断。
