Isawa T, Teshima T, Hirano T, Ebina A, Konno K
Tohoku J Exp Med. 1986 Feb;148(2):169-78. doi: 10.1620/tjem.148.169.
To evaluate mucociliary clearance mechanisms of the lungs, 14 patients with pulmonary interstitial fibrosis and 8 with sarcoidosis were studied by lung function tests and radioaerosol inhalation lung cine-scintigraphy. Although all these patients showed interstitial densities on chest x-rays, only the patients with pulmonary interstitial fibrosis indicated restrictive and diffusion abnormalities by lung function tests and those with sarcoidosis did not show either of these functional abnormalities. Mucociliary clearance mechanisms were well maintained qualitatively and quantitatively in these patients with interstitial lung disease.
为评估肺部的黏液纤毛清除机制,对14例肺间质纤维化患者和8例结节病患者进行了肺功能测试及放射性气溶胶吸入肺动态闪烁扫描研究。尽管所有这些患者胸部X光片均显示间质密度影,但只有肺间质纤维化患者通过肺功能测试表现出限制性和弥散性异常,而结节病患者未表现出任何这些功能异常。这些间质性肺病患者的黏液纤毛清除机制在质量和数量上均保持良好。