Zhang Linlin, Yu Huan, Zhang Jingjing
Radiotherapy Department, Yantai Yuhuangding Hospital, Yantai, Shandong, China.
Gastroenterology, Central Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Br J Hosp Med (Lond). 2024 Nov 30;85(11):1-12. doi: 10.12968/hmed.2024.0412. Epub 2024 Nov 18.
Implementing effective nursing management is particularly critical in the case of elderly gastric cancer (GC) patients receiving chemotherapy, who are more vulnerable to risk events. Therefore, this study explored the effect of intensive nursing management on quality of life (QoL) and mental health in elderly GC patients receiving chemotherapy. A total of 155 elderly patients with GC undergoing chemotherapy in Central Hospital Affiliated to Shandong First Medical University from July 2021 to July 2023 were selected as the study subjects. The sample was divided into two groups according to different nursing methods: 74 patients who received intensive nursing management were classified in the observation group, while 81 patients treated with routine nursing management were classified under the reference group. The QoL, mental health and adverse reactions to chemotherapy were compared between the two groups. Before nursing management was implemented, there was no significant difference in the scores of the quality of life questionnaire-core 30 (QLQ-C30), patient health questionnaire-9 items (PHQ-9), and the Chinese version of the M.D. Anderson Symptom Inventory (MDASI-C) ( > 0.05). After management, in comparison with the reference group, the observation group showed significantly higher scores in each dimension of QLQ-C30, as well as significantly lower scores in PHQ-9 and MDASI-C ( < 0.001). The incidences of gastrointestinal reaction, myelosuppression, neurotoxicity, and hepatorenal damage were lower in the observation group than in the reference group (45.95% vs 70.37%, 40.54% vs 65.43%, 35.14% vs 53.09%, and 33.78% vs 51.25%, respectively; < 0.05). The application of intensive nursing management in treating elderly GC patients during chemotherapy effectively improves their physical and mental states, ameliorates clinical symptoms and enhances the QoL, showing certain clinical application value.
对于接受化疗的老年胃癌患者而言，实施有效的护理管理尤为关键，因为他们更容易遭遇风险事件。因此，本研究探讨了强化护理管理对接受化疗的老年胃癌患者生活质量和心理健康的影响。选取2021年7月至2023年7月在山东第一医科大学附属中心医院接受化疗的155例老年胃癌患者作为研究对象。根据不同护理方法将样本分为两组：74例接受强化护理管理的患者被归为观察组，81例接受常规护理管理的患者被归为对照组。比较两组患者的生活质量、心理健康状况及化疗不良反应。在实施护理管理前，生活质量问卷核心30项（QLQ-C30）、患者健康问卷9项（PHQ-9）及中文版MD安德森症状量表（MDASI-C）的得分差异无统计学意义（>0.05）。管理后，与对照组相比，观察组QLQ-C30各维度得分显著更高，而PHQ-9和MDASI-C得分显著更低（<0.001）。观察组胃肠道反应、骨髓抑制、神经毒性及肝肾损害的发生率低于对照组（分别为45.95%对70.37%、40.54%对65.43%、35.14%对53.09%、33.78%对51.25%；<0.05）。强化护理管理应用于老年胃癌患者化疗期间，可有效改善其身心状态，缓解临床症状，提高生活质量，具有一定的临床应用价值。
